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ChemicalBook >> CAS DataBase List >>L-902,688

L-902,688

L-902,688 Structure
L-902,688 structure
CAS No.
634193-54-7
Chemical Name:
L-902,688
Synonyms
L-902,688;L902688,L 902688;L-902,688 Exclusive;(5R)-5-[(E,3R)-4,4-difluoro-3-hydroxy-4-phenylbut-1-enyl]-1-[6-(2H-tetrazol-5-yl)hexyl]pyrrolidin-2-one;2-Pyrrolidinone, 5-[(1E,3R)-4,4-difluoro-3-hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]-, (5R)-
CBNumber:
CB72591543
Molecular Formula:
C21H27F2N5O2
Molecular Weight:
419.468
MDL Number:
MFCD32661895
MOL File:
634193-54-7.mol
Last updated:2023-06-08 09:03:08
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L-902,688 Properties

storage temp. Store at -20°C
solubility DMF:30.0(Max Conc. mg/mL);71.52(Max Conc. mM)
DMSO:30.0(Max Conc. mg/mL);71.52(Max Conc. mM)
Ethanol:30.0(Max Conc. mg/mL);71.52(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.19(Max Conc. mM)
FDA UNII D17QSK5F4B

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS06,GHS08
Signal word  Danger
Hazard statements  H225-H301+H311+H331-H370
Precautionary statements  P210-P240-P241-P242-P243-P260-P264-P270-P271-P280-P301+P310-P321-P330-P303+P361+P353-P304+P340-P307+P311-P312-P361+P364-P370+P378-P403+P233-P403+P235-P405-P501
NFPA 704
3
0 0

L-902,688 price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10007712 L-902,688 ≥98% 634193-54-7 500μg $112 2024-03-01 Buy
Cayman Chemical 10007712 L-902,688 ≥98% 634193-54-7 1mg $212 2024-03-01 Buy
Cayman Chemical 10007712 L-902,688 ≥98% 634193-54-7 5mg $946 2024-03-01 Buy
Cayman Chemical 10007712 L-902,688 ≥98% 634193-54-7 10mg $1668 2024-03-01 Buy
AK Scientific 1418AH L-902,688(solutioninMeOH) 634193-54-7 5mg $985 2021-12-16 Buy
Product number Packaging Price Buy
10007712 500μg $112 Buy
10007712 1mg $212 Buy
10007712 5mg $946 Buy
10007712 10mg $1668 Buy
1418AH 5mg $985 Buy

L-902,688 Chemical Properties,Uses,Production

Description

Prostaglandin E2 (PGE2) activates four E prostanoid (EP) receptors, EP1-4. EP4 is a Gs protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis. L-902,688 is a highly potent agonist of the human PGE2 receptor, EP4. It demonstrates a Ki value of 0.38 nM and an EC50 value of 0.6 nM and is >4,000-fold selective for EP4 over other EP and prostanoid receptors. L-902,688 induces thermal hyperalgesia when injected into guinea pig forepaw and increases vasodilation of human pulmonary vein.

L-902,688 Preparation Products And Raw materials

Raw materials

Preparation Products

L-902,688 Suppliers

Global( 15)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1991 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 9946 58
amyjetsci 027-59626688 18771149750 sales@amyjet.com China 3004 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24023 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 5021 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Shanghai Hongye Biotechnology Co. Ltd 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
MedBioPharmaceutical Technology Inc 58
cjbscvictory 58
amyjetsci 58
TargetMol Chemicals Inc. 58
Nanjing Tengyi Biotechnology Co., Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
L-902,688 L-902,688 Exclusive (5R)-5-[(E,3R)-4,4-difluoro-3-hydroxy-4-phenylbut-1-enyl]-1-[6-(2H-tetrazol-5-yl)hexyl]pyrrolidin-2-one 2-Pyrrolidinone, 5-[(1E,3R)-4,4-difluoro-3-hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]-, (5R)- L902688,L 902688 634193-54-7 C21H27F2N5O2