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ChemicalBook >> CAS DataBase List >>Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl-

Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl-

Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl- Structure
Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl- structure
CAS No.
1246213-24-0
Chemical Name:
Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl-
Synonyms
Ivacaftor Impurity 1;Ivacaftor impurities5;Ivacaftor carboxylate;Ivacaftor Carboxylic Acid;Ivacaftor Carboxylic Acid Impurity;2-[5-tert-butyl-2-hydroxy-4-[(4-oxo-1H-quinoline-3-carbonyl)amino]phenyl]-2-methylpropanoic acid;2-(5-tert-butyl-2-hydroxy-4-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl)-2-methylpropanoic acid;Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl-;Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl-;Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-alpha,alpha-diMethyl-
CBNumber:
CB72624683
Molecular Formula:
C24H26N2O5
Molecular Weight:
422.48
MDL Number:
MFCD26743488
MOL File:
1246213-24-0.mol
Last updated:2023-04-23 13:52:06
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Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl- Properties

Melting point >213°C (dec.)
Boiling point 624.1±55.0 °C(Predicted)
Density 1.299±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 4.33±0.16(Predicted)
color White to Light Yellow
FDA UNII 38WUF8D79H

Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC I940605 IvacaftorCarboxylicAcid 1246213-24-0 10mg $1390 2021-12-16 Buy
TRC I940605 IvacaftorCarboxylicAcid 1246213-24-0 25mg $3345 2021-12-16 Buy
TRC I940605 IvacaftorCarboxylicAcid 1246213-24-0 1mg $180 2021-12-16 Buy
Usbiological 452811 Ivacaftor Carboxylic Acid 1246213-24-0 2.5mg $368 2021-12-16 Buy
American Custom Chemicals Corporation CHM0387892 2-(5-(TERT-BUTYL)-2-HYDROXY-4-(4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXAMIDO)PHENYL)-2-METHYLPROPANOIC ACID 95.00% 1246213-24-0 5MG $495.53 2021-12-16 Buy
Product number Packaging Price Buy
I940605 10mg $1390 Buy
I940605 25mg $3345 Buy
I940605 1mg $180 Buy
452811 2.5mg $368 Buy
CHM0387892 5MG $495.53 Buy

Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl- Chemical Properties,Uses,Production

Uses

Ivacaftor Carboxylic Acid is an impurity of Ivacaftor (I940600); a drug used in the treatment of cystic fibrosis.

Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl- Suppliers

Global( 29)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14336 58
sgtlifesciences pvt ltd 		+8617013299288 dj@sgtlifesciences.com China 12382 58
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
Nanjing JinruiJiuAn Biotechnology Co., Ltd. 025-58196018 800028039 sales@fartop.net China 2231 55
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Aikon International Limited 025-66113011 13155353615 qzhang@aikonchem.com China 15396 58
Guangzhou Dreampharm Biotechnology Co., Ltd. 17825480238 3008233717@qq.com China 9844 12
Jinan blalong chemical co. LTD 2710913286@.com 1513643261@qq.com China 14253 58
Taizhou Nanfeng Pharmaceutical Research Institute 12345678910 nanfengdrug@163.com China 15323 58
Supplier Advantage
Hubei Jusheng Technology Co.,Ltd. 		58
Standardpharm Co. Ltd. 		58
sgtlifesciences pvt ltd 		58
BOC Sciences 65
Nanjing JinruiJiuAn Biotechnology Co., Ltd. 55
BOC Sciences 65
Aikon International Limited 58
Guangzhou Dreampharm Biotechnology Co., Ltd. 12
Jinan blalong chemical co. LTD 58
Taizhou Nanfeng Pharmaceutical Research Institute 58
Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl- Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-alpha,alpha-diMethyl- 2-(5-tert-butyl-2-hydroxy-4-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl)-2-methylpropanoic acid Ivacaftor Carboxylic Acid 2-[5-tert-butyl-2-hydroxy-4-[(4-oxo-1H-quinoline-3-carbonyl)amino]phenyl]-2-methylpropanoic acid Ivacaftor Impurity 1 Ivacaftor Carboxylic Acid Impurity Ivacaftor carboxylate Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl- Ivacaftor impurities5 1246213-24-0