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ChemicalBook >> CAS DataBase List >>1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo-

1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo-

1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo- Structure
1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo- structure
CAS No.
1214561-09-7
Chemical Name:
1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo-
Synonyms
HPK1-IN-8;1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo-
CBNumber:
CB79970859
Molecular Formula:
C19H17FN6O2S
Molecular Weight:
412.44
MDL Number:
MOL File:
1214561-09-7.mol
Last updated:2023-05-21 10:59:17
Request For Quotation

1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo- Properties

Density 1.53±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
pka 8.27±0.50(Predicted)

1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo- Chemical Properties,Uses,Production

Biological Activity

HPK1-IN-8 is an allosteric, inactive conformation-selective inhibitor of full-length HPK1.

References

[1]. Wang W, et al. Discovery of an Allosteric, Inactive Conformation-Selective Inhibitor of Full-Length HPK1 Utilizing a Kinase Cascade Assay. Biochemistry. 2021 Oct 19;60(41):3114-3124.

1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo- Preparation Products And Raw materials

Raw materials

Preparation Products

1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo- Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.com China 24246 58
Supplier Advantage
Aladdin Scientific 		58
TargetMol Chemicals Inc. 58
1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo- HPK1-IN-8 1214561-09-7