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streptazolin

streptazolin Structure
streptazolin structure
CAS No.
80152-07-4
Chemical Name:
streptazolin
Synonyms
streptazolin;Streptazoline;(+)-Streptazoline;(2aS,4Z)-3β-Hydroxy-4-ethylidene-2aβ,3,4,6,7,7bβ-hexahydro-2-oxa-7a-aza-1H-cyclopenta[cd]indene-1-one;1H-2-Oxa-7a-azacyclopent[cd]inden-1-one, 4-ethylidene-2a,3,4,6,7,7b-hexahydro-3-hydroxy-, (2aS,3S,4Z,7bS)-
CBNumber:
CB81329885
Molecular Formula:
C11H13NO3
Molecular Weight:
207.23
MDL Number:
MOL File:
80152-07-4.mol
Last updated:2023-05-21 10:59:17
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streptazolin Properties

storage temp. Store at -20°C
solubility Dichloromethane: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form A solid

streptazolin price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 27266 Streptazolin 80152-07-4 1mg $65 2024-03-01 Buy
Cayman Chemical 27266 Streptazolin 80152-07-4 5mg $290 2024-03-01 Buy
AK Scientific 5317CS (4S,5S,6E,11S)-6-Ethylidene-5-hydroxy-3-oxa-1-azatricyclo[5.3.1.04,11]undec-7-en-2-one 80152-07-4 5mg $617 2021-12-16 Buy
Product number Packaging Price Buy
27266 1mg $65 Buy
27266 5mg $290 Buy
5317CS 5mg $617 Buy

streptazolin Chemical Properties,Uses,Production

Description

Streptazolin is a fungal metabolite originally isolated from S. viridochromogenes.1 It increases NF-κB activity when used at concentrations ranging from 60 to 130 μg/ml, at least in part, via PI3K signaling.2 Streptazolin enhances TNF-α secretion induced by LPS and enhances IL-8 secretion when used alone or in combination with LPS in THP-1 Blue cells.

References

1. Drautz, H., Zaehner, H., Kupfer, E., et al. Metabolic products of microorganisms. 205. Isolation and structure of streptazolin Helv. Chim. Acta. 64(6),1752-1765(1981).
2. Perry, J.A., Koteva, K., Verschoor, C.P., et al. A macrophage-stimulating compound from a screen of microbial natural products J. Antibiot. (Tokyo) 68(1),40-46(2015).

streptazolin synthesis

271600-60-3
80152-07-4
Synthesis of streptazolin from 3H-Oxazolo[3,4-a]pyridine-3,7(1H)-dione, 8-bromo-1-[(1S)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-butyn-1-yl]-8,8a-dihydro-, (1S,8R,8aR)-

streptazolin Preparation Products And Raw materials

Raw materials

3H-Oxazolo[3,4-a]pyridine-3,7(1H)-dione, 8-bromo-1-[(1S)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-butyn-1-yl]-8,8a-dihydro-, (1S,8R,8aR)-

Preparation Products

streptazolin Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.com China 24246 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
streptazolin (+)-Streptazoline (2aS,4Z)-3β-Hydroxy-4-ethylidene-2aβ,3,4,6,7,7bβ-hexahydro-2-oxa-7a-aza-1H-cyclopenta[cd]indene-1-one Streptazoline 1H-2-Oxa-7a-azacyclopent[cd]inden-1-one, 4-ethylidene-2a,3,4,6,7,7b-hexahydro-3-hydroxy-, (2aS,3S,4Z,7bS)- 80152-07-4