A 1120
- CAS No.
- 1152782-19-8
- Chemical Name:
- A 1120
- Synonyms
- A 1120;A-1120,Inhibitor,inhibit,A 1120,A1120;2-(4-(2-(trifluoromethyl)phenyl)piperidine-1-carboxamido)benzoic acid;Benzoic acid, 2-[[[4-[2-(trifluoromethyl)phenyl]-1-piperidinyl]carbonyl]amino]-
- CBNumber:
- CB82535656
- Molecular Formula:
- C20H19F3N2O3
- Molecular Weight:
- 392.37
- MDL Number:
- MFCD12912393
- MOL File:
- 1152782-19-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Symbol(GHS) | GHS07,GHS09 |
|||||||||
| Signal word | Warning | |||||||||
| Signal word | Warning | |||||||||
| Hazard statements | H302-H317-H319-H400 | |||||||||
| Hazard statements | H302-H317-H319-H400 | |||||||||
| Precautionary statements | P273-P280-P301+P312+P330-P302+P352-P305+P351+P338 | |||||||||
| Precautionary statements | P273-P280-P301+P312+P330-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,N | |||||||||
| Risk Statements | 22-36-43-50/53 | |||||||||
| Safety Statements | 26-36/37-60-61 | |||||||||
| RIDADR | UN 3077 9 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
A 1120 price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A3111 | A1120 ≥98% (HPLC), powder | 1152782-19-8 | 5mg | $120 | 2024-03-01 | Buy |
| Sigma-Aldrich | A3111 | A1120 ≥98% (HPLC), powder | 1152782-19-8 | 25mg | $563 | 2024-03-01 | Buy |
| Tocris | 3793 | A1120 ≥99%(HPLC) | 1152782-19-8 | 50 | $785 | 2021-12-16 | Buy |
| Tocris | 3793 | A1120 ≥99%(HPLC) | 1152782-19-8 | 10 | $186 | 2021-12-16 | Buy |
| TRC | A965350 | A1120 | 1152782-19-8 | 2.5mg | $220 | 2021-12-16 | Buy |
A 1120 Chemical Properties,Uses,Production
Uses
A 1120 is a a nonretinoid RBP4 antagonist, which inhibits formation of cytotoxic bisretinoids in the animal model of enhanced retinal lipofuscinogenesis.
Biochem/physiol Actions
A1120 is a selective non-retinoid ligand for retinol-binding protein 4 (RBP4). RBP4 transports retinol from the liver to extrahepatic tissues and RBP4 lowering is reported to improve insulin sensitivity in mice. A1120 is a high affinity non-retinoid ligand for RBP4 which disrupts the interaction between RBP4 and its binding partner transthyretin (TTR). It binds to the same site as retinol and induces changes in the orientation (compared to the retinol bound form) of loops at the RBP4-TTR interaction interface.A1120 lowers RBP4 and retinol levels in a dose-dependent manner, to a similar extent as seen with fenretinide. However, unlike fenretinide (Sigma# H7779), A1120 does not have beneficial effects on insulin resistance.
storage
Store at RT
A 1120 Preparation Products And Raw materials
Raw materials
Preparation Products
A 1120 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9747 | 58 |
| Henan Weituxi Chemical Technology Co., Ltd. | 0371-63284658 18135795563 | 2885349392@qq.com | China | 9983 | 58 |
| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9414 | 58 |
