ChemicalBook >> CAS DataBase List >>L 2-401
L 2-401
- CAS No.
- 883050-24-6
- Chemical Name:
- L 2-401
- Synonyms
- CS-563;L 2-401;CCG 50014;CCG50014;CCG 50014;CCG-50014 >=98% (HPLC);4-(4-Fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione;4-[(4-Fluorophenyl)methyl]-2-(4-methylphenyl)-1,2,4-thiadiazolidine-3,5-dione;1,2,4-Thiadiazolidine-3,5-dione, 4-[(4-fluorophenyl)methyl]-2-(4-methylphenyl)-;Regulators of G-protein Signaling,Regulator of G-protein Signaling,RGS Protein,CCG-50014,inhibit,CCG50014,Inhibitor
- CBNumber:
- CB82657938
- Molecular Formula:
- C16H13FN2O2S
- Molecular Weight:
- 316.35
- MDL Number:
- MFCD00113783
- MOL File:
- 883050-24-6.mol
Last updated:2023-09-20 16:43:00
| Density | 1.398±0.06 g/cm3 (20 ºC 760 Torr) |
|---|---|
| storage temp. | 2-8°C |
| solubility | DMSO: soluble5mg/mL, clear (warmed) |
| form | powder |
| color | white to beige |
| FDA UNII | RA72G28VE9 |
L 2-401 price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0908 | CCG-50014 ≥98% (HPLC) | 883050-24-6 | 5mg | $122 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0908 | CCG-50014 ≥98% (HPLC) | 883050-24-6 | 25mg | $382 | 2024-03-01 | Buy |
| Cayman Chemical | 10802 | CCG-50014 ≥98% | 883050-24-6 | 1mg | $27 | 2024-03-01 | Buy |
| Cayman Chemical | 10802 | CCG-50014 ≥98% | 883050-24-6 | 5mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 10802 | CCG-50014 ≥98% | 883050-24-6 | 10mg | $146 | 2024-03-01 | Buy |
L 2-401 Chemical Properties,Uses,Production
Description
CCG-50014 is an inhibitor of regulator of G protein signaling 4 (RGS4) (IC50 = 30 nM) and is > 20-fold selective for RGS4 over other RGS proteins. RGS proteins bind to the Gα subunits of activated heterotrimeric G proteins and accelerate the rate of GTP hydrolysis, acting as GTPase-activating proteins. CCG-50014 irreversibly binds and destabilizes RGS4 with no effect on Gα0, while blocking GTPase activity and Gα0-dependent translocation of RGS4 to the membrane.
L 2-401 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 74)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 18521735133 18521732826; | market@aladdin-e.com | China | 25014 | 65 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4153 | 55 |
4-[(4-Fluorophenyl)methyl]-2-(4-methylphenyl)-1,2,4-thiadiazolidine-3,5-dione
CCG 50014
L 2-401
1,2,4-Thiadiazolidine-3,5-dione, 4-[(4-fluorophenyl)methyl]-2-(4-methylphenyl)-
4-(4-Fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione
CCG50014;CCG 50014
CS-563
CCG-50014 >=98% (HPLC)
Regulators of G-protein Signaling,Regulator of G-protein Signaling,RGS Protein,CCG-50014,inhibit,CCG50014,Inhibitor
883050-24-6
Inhibitors