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4-fluoro-2-Methoxy-5-nitroaniline

4-fluoro-2-Methoxy-5-nitroaniline structure

CAS No.: 1075705-01-9

Chemical Name:: 4-fluoro-2-Methoxy-5-nitroaniline

Synonyms: 4-fluoro-2-methoxy;AZD9291 intermediates;uoro-2-methoxy-5-nitroaniL;4-Fluoro-2-mehoxy-5-nitroaniline;4-fluoro-2-Methoxy-5-nitroaniline;4-Fluoro-2-Methoxy-5-nitrobenzenaMine;4-fluoro-2-methoxy-5-nitrophenylamine;4-Fluoro-2-methoxy-5-nitroaniline 95+%;Benzenamine, 4-fluoro-2-methoxy-5-nitro-;4-fluoro-2-Methoxy-5-nitroaniline ISO 9001：2015 REACH

CBNumber:: CB82670450

Molecular Formula:: C7H7FN2O3

Molecular Weight:: 186.14

MDL Number:: MFCD23098941

MOL File:: 1075705-01-9.mol

MSDS File:: SDS

Last updated:2024-05-16 10:38:37

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4-fluoro-2-Methoxy-5-nitroaniline Properties

Melting point	130 °C
Boiling point	354.8±37.0 °C(Predicted)
Density	1.412±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
form	powder to crystal
pka	2.31±0.10(Predicted)
color	Light yellow to Brown
InChI	InChI=1S/C7H7FN2O3/c1-13-7-2-4(8)6(10(11)12)3-5(7)9/h2-3H,9H2,1H3
InChIKey	FYSIGSQCZXQTIH-UHFFFAOYSA-N
SMILES	C1(N)=CC([N+]([O-])=O)=C(F)C=C1OC

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302+H312+H332-H315-H319-H335

Precautionary statements

P261-P271-P280

HS Code

2921420090

NFPA 704

	0
2		0

4-fluoro-2-Methoxy-5-nitroaniline price More Price(30)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	F1246	4-Fluoro-2-methoxy-5-nitroaniline	1075705-01-9	5G	$33	2024-03-01	Buy
TCI Chemical	F1246	4-Fluoro-2-methoxy-5-nitroaniline	1075705-01-9	25G	$98	2024-03-01	Buy
TRC	F472455	4-Fluoro-2-methoxy-5-nitroaniline	1075705-01-9	10g	$140	2021-12-16	Buy
TRC	F472455	4-Fluoro-2-methoxy-5-nitroaniline	1075705-01-9	25g	$275	2021-12-16	Buy
AK Scientific	9516AF	4-Fluoro-2-methoxy-5-nitroaniline	1075705-01-9	100g	$321	2021-12-16	Buy

Product number	Packaging	Price	Buy
F1246	5G	$33	Buy
F1246	25G	$98	Buy
F472455	10g	$140	Buy
F472455	25g	$275	Buy
9516AF	100g	$321	Buy

4-fluoro-2-Methoxy-5-nitroaniline Chemical Properties,Uses,Production

Uses

4-Fluoro-2-methoxy-5-nitroaniline is used as a reagent for preparing the anticancer drug Mereletinib.

Synthesis

4-FLUORO-2-METHOXYANILINE(551 mg, 3.90 mmol) is dissolved in dichloromethane (39.0 mL), concentrated sulfuric acid (1.85 mL) is added dropwise with stirring under ice-cooling, and then concentrated nitric acid (267 μL, 5.85 mmol) is added dropwise. After stirring for 3 hours under ice-cooling, saturated aqueous sodium bicarbonate was added until pH 8 was reached. After washing with saturated aqueous sodium bicarbonate solution, washing with saturated brine, the organic layer was dried over sodium sulfate and evaporated under reduced pressure to obtain 675 mg of the 4-fluoro-2-Methoxy-5-nitroaniline (yield 93%).

4-fluoro-2-Methoxy-5-nitroaniline synthesis

Synthesis of 4-fluoro-2-Methoxy-5-nitroaniline from 4-FLUORO-2-METHOXYANILINE

4-fluoro-2-Methoxy-5-nitroaniline Preparation Products And Raw materials

Raw materials

Preparation Products

N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine AZ 7550

4-fluoro-2-Methoxy-5-nitroaniline Suppliers

Global( 388)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Golden Pharma Co., Limited	+undefined18958062155	sales@zjgoldpharm.com	China	5905	58
Jiangsu Boquan Biotechnology Co., Ltd.	+86-18168774353	boquanshengwu003@boquansw.com	China	248	58
Jinan Dexinjia Bio&Tech Co., Ltd	+86-0531-82375893 +86-15553111391	sales@jndxj.com	China	1188	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12470	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	18214	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21687	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9341	55
Shanghai Yingrui Biopharma Co., Ltd.	+86-21-33585366 - 03@	sales03@shyrchem.com	CHINA	738	60

Supplier	Advantage
Golden Pharma Co., Limited	58
Jiangsu Boquan Biotechnology Co., Ltd.	58
Jinan Dexinjia Bio&Tech Co., Ltd	58
Hebei Mojin Biotechnology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
Shanghai Yingrui Biopharma Co., Ltd.	60

4-Fluoro-2-Methoxy-5-nitroaniline: properties, applications and safety
4-Fluoro-2-Methoxy-5-nitroaniline is a valuable intermediate in organic synthesis and medicinal chemistry, with caution requir....
Dec 12，2023

Preparation of 4-fluoro-2-Methoxy-5-Nitroaniline
4-fluoro-2-Methoxy-5-nitroaniline is an important organic intermediate to synthetize substituted benzene products.
Nov 5，2019

View Lastest Price from 4-fluoro-2-Methoxy-5-nitroaniline manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-09	4-fluoro-2-Methoxy-5-nitroaniline 1075705-01-9	US $5.00-0.10 / KG	1KG	98%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2023-09-25	4-Fluoro-2-Methoxy-5-Nitroaniline 1075705-01-9	US $50.00 / g	1g	99%	2 kg	Anhui Yisheng Technology Co., LTD
2023-08-16	4-Fluoro-2-Methoxy-5-Nitroaniline 1075705-01-9	US $80.00 / KG	1KG	>99%	20tons	Weijer International Trade (Hebei) Co., Ltd

4-fluoro-2-Methoxy-5-nitroaniline
1075705-01-9
US $5.00-0.10 / KG
98%
Henan Fengda Chemical Co., Ltd

4-Fluoro-2-Methoxy-5-Nitroaniline
1075705-01-9
US $50.00 / g
99%
Anhui Yisheng Technology Co., LTD

4-Fluoro-2-Methoxy-5-Nitroaniline
1075705-01-9
US $80.00 / KG
>99%
Weijer International Trade (Hebei) Co., Ltd

4-fluoro-2-Methoxy-5-nitroaniline Spectrum

4-fluoro-2-Methoxy-5-nitroaniline(1075705-01-9)¹HNMR

1075705-01-9(4-fluoro-2-Methoxy-5-nitroaniline)Related Search:

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4-fluoro-2-Methoxy-5-nitroaniline 2-Amino-5-fluoro-4-nitroanisole, 4-Fluoro-5-nitro-o-anisidine 4-Fluoro-2-Methoxy-5-nitrobenzenaMine Benzenamine, 4-fluoro-2-methoxy-5-nitro- 4-fluoro-2-methoxy-5-nitrophenylamine 4-Fluoro-2-methoxy-5-nitroaniline 95+% AZD9291 intermediates uoro-2-methoxy-5-nitroaniL 4-Fluoro-2-mehoxy-5-nitroaniline 4-fluoro-2-Methoxy-5-nitroaniline ISO 9001：2015 REACH 4-fluoro-2-methoxy-5-nitroaniline Molecular Formula: C7H7FN2O3 Molecular Weight: 186.14 4-fluoro-2-methoxy 1075705-01-9 075705-01-9 AZD9291 API 1075705-01-9