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Diethyl bromodifluoromethanephosphonate

Diethyl bromodifluoromethanephosphonate structure

CAS No.: 65094-22-6

Chemical Name:: Diethyl bromodifluoromethanephosphonate

Synonyms: DIETHYL (BROMODIFLUOROMETHYL)PHOSPHONATE;BROMODIFLUOROMETHYL DIETHYLPHOSPHONATE;Diethyl bromodifluoromethanephosphonat;BROMODIFLUOROMETHANE DIETHYL PHOSPHATE;Diethyl bromodifluoromethanephosphonate;Bromodifluoromethyldiethylphosphonate97%;Bromodifluoromethyl diethylphosphonate 97%;Diethyl P-(bromodifluoromethyl)phosphonate;Diethyl (Bromodifluoromethyl)phosphonate >Diethyl [bromo(difluoro)methyl]phosphonate 97%

CBNumber:: CB8333674

Molecular Formula:: C5H10BrF2O3P

Molecular Weight:: 267.01

MDL Number:: MFCD00069118

MOL File:: 65094-22-6.mol

MSDS File:: SDS

Last updated:2024-04-15 18:41:30

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Diethyl bromodifluoromethanephosphonate Properties

Boiling point	40-41 °C/0.05 mmHg (lit.)
Density	1.503 g/mL at 25 °C (lit.)
refractive index	n20/D 1.417(lit.)
Flash point	>230 °F
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Chloroform, Ethyl Acetate
form	liquid
Specific Gravity	1.503
color	colorless
Water Solubility	Not miscible or difficult to mix in water.
BRN	1944045
CAS DataBase Reference	65094-22-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P264-P280a-P305+P351+P338-P321-P332+P313-P337+P313

Hazard Codes

Risk Statements

21/22-36/38-38-36

Safety Statements

26-36/37/39-60-37-23

RIDADR

3278

WGK Germany

Hazard Note

Irritant

TSCA

HazardClass

IRRITANT, IRRITANT-HARMFUL

PackingGroup

III

HS Code

29319090

NFPA 704

	1
2		0

Diethyl bromodifluoromethanephosphonate price More Price(38)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	411361	Diethyl (bromodifluoromethyl)phosphonate 96%	65094-22-6	5g	$102	2024-03-01	Buy
TCI Chemical	D3071	Diethyl (Bromodifluoromethyl)phosphonate >97.0%(GC)	65094-22-6	5g	$38	2024-03-01	Buy
TCI Chemical	D3071	Diethyl (Bromodifluoromethyl)phosphonate >97.0%(GC)	65094-22-6	25g	$149	2024-03-01	Buy
Alfa Aesar	L16715	Diethyl (bromodifluoromethyl)phosphonate, 97%	65094-22-6	1g	$24.65	2024-03-01	Buy
Alfa Aesar	L16715	Diethyl (bromodifluoromethyl)phosphonate, 97%	65094-22-6	5g	$73.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
411361	5g	$102	Buy
D3071	5g	$38	Buy
D3071	25g	$149	Buy
L16715	1g	$24.65	Buy
L16715	5g	$73.65	Buy

Diethyl bromodifluoromethanephosphonate Chemical Properties,Uses,Production

Uses

Diethyl (bromodifluoromethyl)phosphonate is used as a reactant for the preparation of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat3), synthesis of Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory difluoromethylphosphonic acid derivatives via multi step synthesis with Suzuki coupling and resolution as key steps and P-C bond cleavage on basic hydrolysis.

Uses

Efficient difluoroalkylation of aryl boronic acids via palladium catalysis. Novel, moisture-stable bromodifluoromethylated phosphonate, ester, and amide. Efficient coupling with aryl boronic acids via Pd catalysis.

Synthesis Reference(s)

The Journal of Organic Chemistry, 49, p. 3437, 1984 DOI: 10.1021/jo00192a056

Diethyl bromodifluoromethanephosphonate Preparation Products And Raw materials

Raw materials

Preparation Products

2'-(DIFLUOROMETHOXY)ACETOPHENONE 98 DIFLUOROMETHYLPHOSPHONIC ACID DIETHYL ESTER 1H-Benzimidazole-2-methanol, 1-(difluoromethyl)- Benzaldehyde, 2-bromo-6-(difluoromethoxy)- Phosphonic acid, P-[(4-bromophenyl)difluoromethyl]-, diethyl ester

benzyl(difluoroMethyl)sulfane 4-(Difluoromethoxy)-2-fluorobromobenzene

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Diethyl bromodifluoromethanephosphonate Suppliers

Global( 232)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3012	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	7019	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Shanghai Worldyang Chemical Co.,Ltd.	,+86-21-56795779; +8613651600618	sales@worldyachem.com	China	879	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58

Supplier	Advantage
Zibo Hangyu Biotechnology Development Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Nanjing ChemLin Chemical Industry Co., Ltd.	60
career henan chemical co	58
Jinan Carbotang Biotech Co.,Ltd.	58
Accela ChemBio Inc.	58
Shanghai Worldyang Chemical Co.,Ltd.	58
Hubei xin bonus chemical co. LTD	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58

View Lastest Price from Diethyl bromodifluoromethanephosphonate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-05-10	bromodifluoromethane diethyl phosphate 65094-22-6	US $0.10-0.10 / kg	0.005kg	99.99%	20 tons	Zibo Hangyu Biotechnology Development Co., Ltd
2022-10-10	Diethyl bromodifluoromethanephosphonate 65094-22-6	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2021-07-02	Diethyl bromodifluoromethanephosphonate 65094-22-6	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

bromodifluoromethane diethyl phosphate
65094-22-6
US $0.10-0.10 / kg
99.99%
Zibo Hangyu Biotechnology Development Co., Ltd

Diethyl bromodifluoromethanephosphonate
65094-22-6
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

Diethyl bromodifluoromethanephosphonate
65094-22-6
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

Diethyl bromodifluoromethanephosphonate Spectrum

Diethyl bromodifluoromethanephosphonate(65094-22-6)¹HNMR Diethyl bromodifluoromethanephosphonate(65094-22-6)IR Diethyl bromodifluoromethanephosphonate(65094-22-6)FT-IR

65094-22-6(Diethyl bromodifluoromethanephosphonate)Related Search:

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DIETHYL PHOSPHATE METHYLPHOSPHONIC ACID Diethyl methylphosphonate

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BROMODIFLUOROMETHANE DIETHYL PHOSPHATE Diethyl bromodifluoromethanephosphonate Bromodifluoromethyl diethyl phosphonate~Diethyl bromodifluoromethanephosphonate BromodifluoromethylphosphonicAcidDiethylEsterDiethylBromodifluoromethylphosphonate Bromodifluoromethyl diethylphosphonate 97% Bromodifluoromethyldiethylphosphonate97% 1-[[Bromo(difluoro)methyl]-ethoxyphosphoryl]oxyethane Phosphonic acid,P-(broModifluoroMethyl)-, diethyl ester (Bromodifluoromethyl)phosphonic acid diethyl ester Diethyl [bromo(difluoro)methyl]phosphonate 97% Diethyl bromodifluoromethanephosphonat Diethyl (Bromodifluoromethyl)phosphonate > BROMODIFLUOROMETHYL DIETHYLPHOSPHONATE DIETHYL (BROMODIFLUOROMETHYL)PHOSPHONATE Diethyl P-(bromodifluoromethyl)phosphonate 65094-22-6 65904-22-6 BrCF2POOC2H52 C5H10O3BrF2P C5H10BrF2O3P C-C Bond Formation Horner-Wadsworth-Emmons Reagents Olefination Synthetic Reagents C-C Bond Formation Horner-Wadsworth-Emmons Reagents Olefination