ChemicalBook >> CAS DataBase List >>EC 1.1.1.42

EC 1.1.1.42

CAS No.
9028-48-2
Chemical Name:
EC 1.1.1.42
Synonyms
IDH;ICDH;IDH1;MGC55806;MGC171441;MGC174090;EC 1.1.1.42;EC 1.1.1.42 TYPE I;EC 1.1.1.42 TYPE IV;:THREO-DS-ISOCITRATE
CBNumber:
CB8395171
Molecular Formula:
NULL
Molecular Weight:
0
MDL Number:
MFCD00131420
MOL File:
Mol file
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

EC 1.1.1.42 Properties

storage temp. 2-8°C
form solution (clear)
color yellow-brown

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280-P302+P352-P362+P364
WGK Germany  3
10
HS Code  3507909090

EC 1.1.1.42 price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich I5036 Isocitrate Dehydrogenase 1 (NADP+) human recombinant, expressed in E. coli, lyophilized powder, ≥80?units/mg protein 9028-48-2 100μg $517 2024-03-01 Buy
Sigma-Aldrich I2411 Isocitrate Dehydrogenase 1 (NADP+) human recombinant, expressed in Sf9 cells, ≥90% (SDS-PAGE) 9028-48-2 10μg $717 2024-03-01 Buy
Sigma-Aldrich I1877 Isocitric Dehydrogenase (NADP) from porcine heart Type I, 0.5-3.0 unit/mg solid (plus numerous enzyme activities associated with porcine heart) 9028-48-2 500mg $130.8 2024-03-01 Buy
Sigma-Aldrich I1877 Isocitric Dehydrogenase (NADP) from porcine heart Type I, 0.5-3.0 unit/mg solid (plus numerous enzyme activities associated with porcine heart) 9028-48-2 1g $393 2024-03-01 Buy
Sigma-Aldrich I2002 Isocitric Dehydrogenase (NADP) from porcine heart Type IV, buffered aqueous glycerol solution, 3-20 units/mg protein 9028-48-2 25mg $112 2024-03-01 Buy
Product number Packaging Price Buy
I5036 100μg $517 Buy
I2411 10μg $717 Buy
I1877 500mg $130.8 Buy
I1877 1g $393 Buy
I2002 25mg $112 Buy

EC 1.1.1.42 Chemical Properties,Uses,Production

Uses

Human Isocitrate Dehydrogenase (IDH1) is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. It may be useful as a biomarker for diagnosis and prognosis prediction of non-small cell lung cancer .

General Description

Isocitrate dehydrogenase 1 (IDH1) gene is located on human chromosome 2q33. IDH1 is present in the cytoplasm and peroxisomes. It is expressed at high levels in the mammalian liver. IDH1 consists of a C-terminal tripeptide peroxisome, that targets the signal one sequence.

Biochem/physiol Actions

Isocitrate dehydrogenase 1 (IDH1) help in the oxidative carboxylation of isocitrate to α-ketoglutarate, that results in the formation of reduced nicotinamide adenine dinucleotide phosphate (NADPH). It participates in lipid metabolism and glucose sensing. Suppressing IDH1 in pancreatic islets affects the insulin secretion, induced by glucose and leads to increase in lactate production.

EC 1.1.1.42 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 56)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49391 58
Creative Enzymes
1-516-855-7709 info@creative-enzymes.com United States 8748 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Adamas Reagent, Ltd. 400-6009262 16621234537 zhangsn@titansci.com China 14113 59
Nanjing Sunlida Biological Technology Co., Ltd. 025-57798810 sales@sunlidabio.com China 3750 55
Shanghai BeiZhuo Biotech Co., Ltd. 021-61119791,13386096464 bzswkf@foxmail.com China 3924 50
Shanghai JONLN Reagent Co., Ltd. 400-0066400 13621662912 422131432@qq.com China 9986 55

View Lastest Price from EC 1.1.1.42 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
EC 1.1.1.42 pictures 2019-07-06 EC 1.1.1.42
9028-48-2
US $1.00 / kg 1kg 95%-99% 1000kg Career Henan Chemical Co
  • EC 1.1.1.42 pictures
  • EC 1.1.1.42
    9028-48-2
  • US $1.00 / kg
  • 95%-99%
  • Career Henan Chemical Co
THREO-DS-ISOCITRATE: NADP+ OXIDOREDUCTASE THREO-DS-ISOCITRATE: NADP(+) OXIDOREDUCTASE[DECARBOXYLATING] THREO-DS-ISOCITRATE: NADP(+) OXIDOREDUCTASE[DECARBOXYLATING] TYPE I THREO-DS-ISOCITRATE: NADP(+) OXIDOREDUCTASE[DECARBOXYLATING] TYPE IV isocitrate dehydrogenase from porcine heart ICDH ISOCITRIC DEHYDROGENASE (NADP) ISOCITRIC DEHYDROGENASE (NADP) TYPE I ISOCITRIC DEHYDROGENASE (NADP) TYPE IV ISOCITRATE DEHYDROGENASE EC 1.1.1.42 EC 1.1.1.42 TYPE I EC 1.1.1.42 TYPE IV ISOCITRAT DEHYDROGENASE FROM PORCINE HEA RT, 3-8 U/MG ISOCITRIC DEHYDROGENASE TYPE IV FROM*POR CINE HEART ISOCITRATE DEHYDROGENASE FROM PORCINE HE ART, ~10 U/MG ISOCITRIC DEHYDROGENASE TYPE I CRUDE*FRO M PORCINE H isocitric dehydrogenase (nadp) from porcine heart Recombinant Isocitrate Dehydrogenase isocitric dehydrogenase ICDH, threo-Ds-Isocitrate: NADP+ oxidoreductase Isocitric Dehydrogenase (NADP) from porcine heart,threo-Ds-Isocitrate: NADP+ oxidoreductase, ICDH Isocitrate dehydrogenase (NAD+) recombinant from Yeast, 50% glycerol solution rICDH (NADP), threo-Ds-Isocitrate: NAD oxidoreductase (decarboxylating) rICDH (NAD), threo-Ds-Isocitrate: NAD oxidoreductase (decarboxylating) IsoCltrate dehydrogenase TPN-specific isocitrate dehydrogenase TPN-linked isocitrate dehydrogenase TPN-isocitrate dehydrogenase TPN-dependent isocitrate dehydrogenase Oxalosuccinic decarboxylase Isocitrate Dehydrogenase preparation porcine heart isocitric dehydrogenase type I crude*from porcine Dehydrogenase, isocitrate (nicotinamide adenine dinucleotide phosphate) ISOCITRIC DEHYDROGENASE HIGHLY PURIFIED FROM PORCIN Isocitrate Dehydrogenase 1 (NADP+) huMan IDH IDH1 Isocitrate Dehydrogenase Cytoplasmic MGC171441 MGC174090 MGC55806 Isocitric Dehydrogenase (NADP), Bacillus subtilis, recombinant from E. coli Isocitric Dehydrogenase (NADP) from porcine heart Type IV, buffered aqueous glycerol solution, 3-20 units/mg protein NADP-specific isocitric dehydyrogenase NADPH-dependent isocitrate dehydrogenase Isocitrate Dehydrogenase (NADP+) from Bacteria, Recombinant Native Porcine Isocitric Dehydrogenase (NADP) Isocitrate Dehydrogenase (NADP+) from Yeast, Recombinant Recombinant Human IDH1 C-his8 Protein, His Tag Recombinant Human IDH1 Protein, His Tag Isocitrate dehydrogenase from Bacillus subtilis, Recombinant :THREO-DS-ISOCITRATE Isocitrate dehydrogenas 9028-48-2 1.1.x.x Acting on hydroxyl groups Biochemicals and Reagents BioChemical