REVERSIN 121
- CAS No.
- 174630-04-7
- Chemical Name:
- REVERSIN 121
- Synonyms
- REVERSIN 121;BOC-ASP(OBZL)-LYS(Z)-OTBU;L-Lysine, N-[(1,1-dimethylethoxy)carbonyl]-L-α-aspartyl-N6-[(phenylmethoxy)carbonyl]-, 2-(1,1-dimethylethyl) 1-(phenylmethyl) ester
- CBNumber:
- CB8699257
- Molecular Formula:
- C34H47N3O9
- Molecular Weight:
- 641.75
- MDL Number:
- MFCD03788012
- MOL File:
- Mol file
Last updated:2023-04-23 13:52:06
REVERSIN 121 price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | R1276 | Reversin 121 ≥97% (HPLC), powder | 174630-04-7 | 3mg | $583 | 2024-03-01 | Buy |
| Cayman Chemical | 18603 | Reversin 121 ≥98% | 174630-04-7 | 500μg | $34 | 2024-03-01 | Buy |
| Cayman Chemical | 18603 | Reversin 121 ≥98% | 174630-04-7 | 1mg | $59 | 2024-03-01 | Buy |
| Cayman Chemical | 18603 | Reversin 121 ≥98% | 174630-04-7 | 5mg | $198 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | PEP0004566 | REVERSIN 121 95.00% | 174630-04-7 | 3MG | $874.34 | 2021-12-16 | Buy |
REVERSIN 121 Chemical Properties,Uses,Production
Description
Reversin 121 is a hydrophobic peptide chemosensitizer that can reverse P-glycoprotein-mediated multidrug resistance. It binds to the P-glycoprotein multidrug transporter (MDR1) with a Kd value of 77 nM. Reversin 121 modulates P-glycoprotein ATPase activity in Sf9 insect cell membranes expressing human MDR1, plasma membrane vesicles from multidrug-resistant cells, and reconstituted proteoliposomes as well as in a variety of MDR1-expressing intact tumor cells.
Uses
Reversin 121 has been used to determine the activity of P-glycoprotein in human retinal pigment epithelium.
General Description
Reversin 121 is an analog of reversin and a dipeptide derivative.
Biochem/physiol Actions
Peptide chemosensitizer, inhibitor of P-glycoprotein.
REVERSIN 121 Preparation Products And Raw materials
Raw materials
Preparation Products
REVERSIN 121 Suppliers
Global( 32)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 | eric@peptidego.com | China | 6347 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| Hangzhou Sinoda Pharmaceutical Technology Co. LTD | 0571-87213919 17306812703 | 3007955328@qq.com | China | 5950 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.com | China | 24246 | 58 |
REVERSIN 121
BOC-ASP(OBZL)-LYS(Z)-OTBU
L-Lysine, N-[(1,1-dimethylethoxy)carbonyl]-L-α-aspartyl-N6-[(phenylmethoxy)carbonyl]-, 2-(1,1-dimethylethyl) 1-(phenylmethyl) ester
174630-04-7
C34H47N3O9
Enzymes, Inhibitors, and Substrates
Enzyme Inhibitors
Enzyme Inhibitors by Enzyme
P-Glycoprotein
P to Q
Biochemicals and Reagents
BioChemical