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ChemicalBook >> CAS DataBase List >>1H-Pyrido[3,4-b]indole, 1-[2,6-difluoro-4-[[1-(3-fluoropropyl)-3-azetidinyl]oxy]phenyl]-2-(2-fluoro-2-methylpropyl)-2,3,4,9-tetrahydro-3-methyl-, (1R,3R)-

1H-Pyrido[3,4-b]indole, 1-[2,6-difluoro-4-[[1-(3-fluoropropyl)-3-azetidinyl]oxy]phenyl]-2-(2-fluoro-2-methylpropyl)-2,3,4,9-tetrahydro-3-methyl-, (1R,3R)-

1H-Pyrido[3,4-b]indole, 1-[2,6-difluoro-4-[[1-(3-fluoropropyl)-3-azetidinyl]oxy]phenyl]-2-(2-fluoro-2-methylpropyl)-2,3,4,9-tetrahydro-3-methyl-, (1R,3R)- Structure
1H-Pyrido[3,4-b]indole, 1-[2,6-difluoro-4-[[1-(3-fluoropropyl)-3-azetidinyl]oxy]phenyl]-2-(2-fluoro-2-methylpropyl)-2,3,4,9-tetrahydro-3-methyl-, (1R,3R)- structure
CAS No.
1953132-75-6
Chemical Name:
1H-Pyrido[3,4-b]indole, 1-[2,6-difluoro-4-[[1-(3-fluoropropyl)-3-azetidinyl]oxy]phenyl]-2-(2-fluoro-2-methylpropyl)-2,3,4,9-tetrahydro-3-methyl-, (1R,3R)-
Synonyms
GNE-149;1H-Pyrido[3,4-b]indole, 1-[2,6-difluoro-4-[[1-(3-fluoropropyl)-3-azetidinyl]oxy]phenyl]-2-(2-fluoro-2-methylpropyl)-2,3,4,9-tetrahydro-3-methyl-, (1R,3R)-
CBNumber:
CB89306691
Molecular Formula:
C28H33F4N3O
Molecular Weight:
503.57
MDL Number:
MOL File:
1953132-75-6.mol
Last updated:2023-03-31 09:12:58
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1H-Pyrido[3,4-b]indole, 1-[2,6-difluoro-4-[[1-(3-fluoropropyl)-3-azetidinyl]oxy]phenyl]-2-(2-fluoro-2-methylpropyl)-2,3,4,9-tetrahydro-3-methyl-, (1R,3R)- Properties

Boiling point 539.9±50.0 °C(Predicted)
Density 1.228±0.06 g/cm3(Predicted)
pka 17.30±0.60(Predicted)

1H-Pyrido[3,4-b]indole, 1-[2,6-difluoro-4-[[1-(3-fluoropropyl)-3-azetidinyl]oxy]phenyl]-2-(2-fluoro-2-methylpropyl)-2,3,4,9-tetrahydro-3-methyl-, (1R,3R)- Chemical Properties,Uses,Production

Description

GNE-149 is a full antagonist and efficient degrader of Estrogen receptor alpha for ER+ breast cancer.

1H-Pyrido[3,4-b]indole, 1-[2,6-difluoro-4-[[1-(3-fluoropropyl)-3-azetidinyl]oxy]phenyl]-2-(2-fluoro-2-methylpropyl)-2,3,4,9-tetrahydro-3-methyl-, (1R,3R)- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Pyrido[3,4-b]indole, 1-[2,6-difluoro-4-[[1-(3-fluoropropyl)-3-azetidinyl]oxy]phenyl]-2-(2-fluoro-2-methylpropyl)-2,3,4,9-tetrahydro-3-methyl-, (1R,3R)- Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Supplier Advantage
Aladdin Scientific 		58
1H-Pyrido[3,4-b]indole, 1-[2,6-difluoro-4-[[1-(3-fluoropropyl)-3-azetidinyl]oxy]phenyl]-2-(2-fluoro-2-methylpropyl)-2,3,4,9-tetrahydro-3-methyl-, (1R,3R)- GNE-149 1953132-75-6 C28H33F4N3O