Decahydro-1-methyl-5,7-diphenyl-6-(3,4,5,6-tetrahydropyridin-2-yl)quinoline

Decahydro-1-methyl-5,7-diphenyl-6-(3,4,5,6-tetrahydropyridin-2-yl)quinoline structure

CAS No.: 6887-36-1

Chemical Name:: Decahydro-1-methyl-5,7-diphenyl-6-(3,4,5,6-tetrahydropyridin-2-yl)quinoline

Synonyms: Lobinaline;Decahydro-1-methyl-5,7-diphenyl-6-(3,4,5,6-tetrahydropyridin-2-yl)quinoline;Quinoline, decahydro-1-methyl-5,7-diphenyl-6-(3,4,5,6-tetrahydro-2-pyridinyl)-, (4aR,5R,6R,7S,8aR)-

CBNumber:: CB92319804

Molecular Formula:: C27H34N2

Molecular Weight:: 386.57

MDL Number:

MOL File:: 6887-36-1.mol

Last updated:2023-07-14 17:47:56

Request For Quotation

Decahydro-1-methyl-5,7-diphenyl-6-(3,4,5,6-tetrahydropyridin-2-yl)quinoline Properties

Melting point	94-5°C
Boiling point	522.6±50.0 °C(Predicted)
Density	1.14±0.1 g/cm3(Predicted)
pka	9.81±0.70(Predicted)

Decahydro-1-methyl-5,7-diphenyl-6-(3,4,5,6-tetrahydropyridin-2-yl)quinoline Chemical Properties,Uses,Production

Description

This alkaloid was first isolated by Manske from Lobelia cardinalis L. It crystallizes with difficulty from EtOH yielding colourless prisms and has [o:l54 + 22.3° (CHCI 3). The hydrochloride sesquihydrate has m.p. 220°C. Oxidation of the alkaloid with KMn04 yields benzoic acid. Pharmacologically, the alkaloid shows few, if any, of the typical characteristics of lobeline (q.v.).

References

Manske., Can. 1. Res., 16B, 445 (1938)
Pharmacology:
See pharmacological note made by Unna in the above reference.
Biosynthesis:
Gupta, Spenser., Chern. Commull., 893 (1966)

Decahydro-1-methyl-5,7-diphenyl-6-(3,4,5,6-tetrahydropyridin-2-yl)quinoline Preparation Products And Raw materials

Raw materials

Preparation Products

Decahydro-1-methyl-5,7-diphenyl-6-(3,4,5,6-tetrahydropyridin-2-yl)quinoline Lobinaline Quinoline, decahydro-1-methyl-5,7-diphenyl-6-(3,4,5,6-tetrahydro-2-pyridinyl)-, (4aR,5R,6R,7S,8aR)- 6887-36-1 C28H38ON2