ChemicalBook >> CAS DataBase List >>m-PEG7-aldehyde

m-PEG7-aldehyde

CAS No.
1058691-77-2
Chemical Name:
m-PEG7-aldehyde
Synonyms
mPEG7-CHO;MPEG7-ALD;mPEG7-pAld;MPEG7-CH2CH2CHO;m-PEG9-aldehyde;m-PEG7-aldehyde;M-PEG6-aldehyde;m-PEG6-CH2CH2CHO;4,7,10,13,16,19,22-Heptaoxatricosanal
CBNumber:
CB93062585
Molecular Formula:
C16H32O8
Molecular Weight:
352.42
MDL Number:
MFCD28976707
MOL File:
1058691-77-2.mol
Last updated:2023-04-23 13:52:06

m-PEG7-aldehyde Properties

solubility Soluble in Water, DMSO, DCM, DMF

m-PEG7-aldehyde price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC P999633 m-PEG7-aldehyde 1058691-77-2 50mg $285 2021-12-16 Buy
TRC P999633 m-PEG7-aldehyde 1058691-77-2 5mg $45 2021-12-16 Buy
BroadPharm BP-22802 m-PEG7-aldehyde 95% 1058691-77-2 100mg $270 2021-12-16 Buy
Apolloscientific BIPG1576 m-PEG7-aldehyde 1058691-77-2 100mg $526 2021-12-16 Buy
BroadPharm BP-22802 m-PEG7-aldehyde 95% 1058691-77-2 500mg $600 2021-12-16 Buy
Product number Packaging Price Buy
P999633 50mg $285 Buy
P999633 5mg $45 Buy
BP-22802 100mg $270 Buy
BIPG1576 100mg $526 Buy
BP-22802 500mg $600 Buy

m-PEG7-aldehyde Chemical Properties,Uses,Production

Description

m-PEG7-aldehyde is a PEG reagent containing an aldehyde group. Aldehyde can react with hydrazide and aminooxy groups for labeling and crosslinking carbonyls.

Biological Activity

M-PEG7-aldehyde is a non-cleavable ADC linker for antibody drug conjugate (ADC) synthesis,it is also a PEG-based PROTAC linker, which can be used for PROTAC synthesis.

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

target

Non-cleavable

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PEGs

m-PEG7-aldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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m-PEG7-aldehyde MPEG7-ALD mPEG7-CHO m-PEG9-aldehyde MPEG7-CH2CH2CHO mPEG7-pAld m-PEG6-CH2CH2CHO 4,7,10,13,16,19,22-Heptaoxatricosanal M-PEG6-aldehyde 1058691-77-2 peg