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2'-O-Methylcytidine

2'-O-Methylcytidine structure

CAS No.: 2140-72-9

Chemical Name:: 2'-O-Methylcytidine

Synonyms: 4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one;OMe-rC;2'-OMe-C;2'-OMe-rC;2'-OMe-Cr;2'-OMe Cytidine;2'-OMe-cytidine;2'-O-METHYLCYTIDINE;2'-O-Methylcytidine;2'-O-Methyl-D-cytidine

CBNumber:: CB9324099

Molecular Formula:: C10H15N3O5

Molecular Weight:: 257.24

MDL Number:: MFCD11519076

MOL File:: 2140-72-9.mol

MSDS File:: SDS

Last updated:2024-03-28 13:39:29

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2'-O-Methylcytidine Properties

Melting point	252-253 C
Boiling point	506.0±60.0 °C(Predicted)
Density	1.68±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility	Soluble in DMSO.
pka	13.37±0.70(Predicted)
form	Powder
color	White to Off-white
InChI	InChI=1S/C10H15N3O5/c1-17-8-7(15)5(4-14)18-9(8)13-3-2-6(11)12-10(13)16/h2-3,5,7-9,14-15H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,9-/m1/s1
InChIKey	RFCQJGFZUQFYRF-ZOQUXTDFSA-N
SMILES	OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](OC)[C@@H]1O
CAS DataBase Reference	2140-72-9(CAS DataBase Reference)
FDA UNII	5XD9IH2G27

SAFETY

Risk and Safety Statements

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-24/25
WGK Germany	3
HS Code	29349990

2'-O-Methylcytidine price More Price(21)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	M2317	2'-O-Methylcytidine >98.0%(HPLC)(T)	2140-72-9	200mg	$47	2024-03-01	Buy
TCI Chemical	M2317	2'-O-Methylcytidine >98.0%(HPLC)(T)	2140-72-9	1g	$185	2024-03-01	Buy
Alfa Aesar	J65528	2'-O-Methylcytidine, 99%	2140-72-9	1g	$64.65	2024-03-01	Buy
Usbiological	296261	2'-O-Methylcytidine	2140-72-9	300mg	$333	2021-12-16	Buy
TRC	M294660	2’-O-MethylCytidine	2140-72-9	5g	$480	2021-12-16	Buy

Product number	Packaging	Price	Buy
M2317	200mg	$47	Buy
M2317	1g	$185	Buy
J65528	1g	$64.65	Buy
296261	300mg	$333	Buy
M294660	5g	$480	Buy

2'-O-Methylcytidine Chemical Properties,Uses,Production

Description

2'-O-Methylcytidine is a nucleoside with a hydroxyl group on the 2' carbon, making it an effective viral replication inhibitor. 2'-O-Methylcytidine is also metabolized by nucleotide salvage pathways and may be able to bind to the response element on DNA, which could inhibit protein synthesis in cancer cells. It is an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50 = 3.8 μM). It inhibits HCV replication in a replicon assay (IC50 = 21.2 μM).

Chemical Properties

White powder

Uses

Cytidine analog.

Uses

2'-O-Methylcytidine is used in the preparation of nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase.

Definition

ChEBI: 2'-O-methylcytidine is a methylcytidine.

2'-O-Methylcytidine synthesis

Synthesis of 2'-O-Methylcytidine from 1,3,5-Tri-O-benzoyl-2-O-methyl-D-ribose

2'-O-Methylcytidine Preparation Products And Raw materials

Raw materials

Preparation Products

3-METHYL URIDINE

2'-O-Methylcytidine Suppliers

Global( 236)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Yunbio Tech Co.,Ltd.	+86-010-60605551 +86-18046518538	yunbiochem@126.com	China	321	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	18222	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Nanjing Baifuli Technology Co., Ltd.	+86-15335185688	sales@unisyn.cn	CHINA	332	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58

Supplier	Advantage
Yunbio Tech Co.,Ltd.	58
LEAPCHEM CO., LTD.	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
career henan chemical co	58
Nanjing Baifuli Technology Co., Ltd.	58
Hubei xin bonus chemical co. LTD	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58

View Lastest Price from 2'-O-Methylcytidine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-03-29	2'-O-Methylcytidine 2140-72-9	US $6.00-1.00 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2024-02-06	2'-O-Methylcytidine 2140-72-9	US $0.00 / KG	1KG	98%	300KG per month	Yunbio Tech Co.,Ltd.
2023-04-04	2'-O-Methylcytidine 2140-72-9	US $0.00-0.00 / kg	1kg	98%	500kg per month	Zhejiang Hengkang Pharmaceutical Co., Ltd.

2'-O-Methylcytidine
2140-72-9
US $6.00-1.00 / KG
99%
Henan Fengda Chemical Co., Ltd

2'-O-Methylcytidine
2140-72-9
US $0.00 / KG
98%
Yunbio Tech Co.,Ltd.

2'-O-Methylcytidine
2140-72-9
US $0.00-0.00 / kg
98%
Zhejiang Hengkang Pharmaceutical Co., Ltd.

2'-O-Methylcytidine Spectrum

2'-O-Methylcytidine(2140-72-9)¹HNMR

2140-72-9(2'-O-Methylcytidine)Related Search:

(Trifluoromethoxy)benzene Anisole Methoxyacetic acid 4-Methoxybenzoic acid p-Anisidine

p-Anisaldehyde Methoxydiethylborane POLY(ETHYLENE GLYCOL) METHYL ETHER ACRYLATE 5-METHYLCYTIDINE,5-METHYLCYTIDINE, 98.0+%(LC)(T) 2'-O-Methyl-N4-Benzoyl-5'-O-DMT-Cytidine

(R)-(-)-TETRAHYDROFURFURYL ALCOHOL (S)-(+)-1-DIMETHYLAMINO-2-PROPANOL 3-Methylcytidine 2''-METHYLCYTIDINE,2'-C-METHYLCYTIDINE 2''-DEOXY-5-METHYLCYTIDINE (5-METHYL-2''-DEOXYCYTIDINE),2'-DEOXY-5-METHYLCYTIDINE

N4-BENZOYL-2'-O-METHYLCYTIDINE 2'-O-Methyl-N4-Acetyl-5'-O-DMT-Cytidine N4-Acetyl-2'-O-Methyl-cytidine

1of4

2'-OMe-C 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-3-methoxy-5-methylol-tetrahydrofuran-2-yl]pyrimidin-2-one 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidin-2-one 4-azanyl-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxy-oxolan-2-yl]pyrimidin-2-one 2'-OMe Cytidine 4-aMino-1-[(2R,3R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)-3-Methoxyoxolan-2-yl]-1,2-dihydropyriMidin-2-one 2'-O-Methylcytidine, >=99% 2'-O-METHYLCYTIDINE 2''-(O-METHYL)-CYTIDINE, HPLC PURIFIED, 98% PURE WITH HPLC UV CHROMATOGRAM 2'-O-Methylcytidineanhydrous 2'-O-Methyl-D-cytidine 2'-O-Methylcytidine, >98.0%(HPLC) 2'-O-Methylcytidine> 2'-OMe-rC 2'-O-Methylcytidine USP/EP/BP 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-1,2-dihydropyrimidin-2-one 2'-OMe-Cr 2’-O-Methyl cytidine, RNA nucleoside Cm 4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one OMe-rC 2'-O-Methylcytidine 2'-OMe-cytidine 2140-72-9 Nucleosides, Nucleotides, Oligonucleotides Nucleoside Analogs BioChemical Biochemicals and Reagents Bases & Related Reagents Carbohydrates & Derivatives Heterocycles Nucleotides Nucleosides, Nucleotides, Oligonucleotides Biochemicals and Reagents Nucleoside Analogs Nucleosides Modified（deoxy）nucleoside Nucleosides-2'-OMe Nucleosides