5-Bromo-4-cyclopropyl-6-methoxypyrimidine 化学特性,用途語,生産方法
合成
To a solution of 4-cyclopropyl-6-methoxypyrimidine (1.6 g, 10.7 mmol) in EtOH (10 mL) was added Bn (1.87 g, 11.7 mmol) at -20 °C. The resulting mixture was slowly warmed to room temperature and stirred at the same temperature for 16 h. Solvent was removed under reduced pressure and the residue dissolved in EtOAc and washed with saturated Na2C03, water and brine. The organic layer was dried over Na2SO4 and concentrated to give 5-bromo-4-cyclopropyl-6-methoxypyrimidine (2.3 g).
5-Bromo-4-cyclopropyl-6-methoxypyrimidine 上流と下流の製品情報
原材料
準備製品