Mycophenolic acid manufacturers and suppliers

Mycophenolic acid suppliers

Properties

Melting point:: 141°C

Boiling point:: 419.24°C (rough estimate)

Density: 1.2300 (rough estimate)

vapor pressure: 0Pa at 22℃

refractive index: 1.5200 (estimate)

Flash point:: 2℃

storage temp.: Sealed in dry,Store in freezer, under -20°C

solubility: methanol: 50 mg/mL, clear, colorless to faintly yellow

form: powder

pka: 4.5(at 25℃)

color: white to white with yellow cast

Water Solubility: 13mg/L(25 ºC)

Merck: 14,6327

BRN: 1295848

BCS Class: 2?

Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

LogP: -1.83-2.28 at 25℃ and pH5-9

Dissociation constant: 4.58-8.05 at 22.5-25℃

Safety Information

Symbol(GHS): GHS07,GHS08,GHS09

Signal word: Danger

Hazard statements: H302-H341-H360D-H372-H410

Precautionary statements: P201-P202-P260-P273-P301+P312-P308+P313

Hazard Codes: Xn,N,T,F

Risk Statements: 22-61-40-68-50/53-48/25-52/53-36-20/21/22-11

Safety Statements: 53-45-36/37-61-22-26-16

RIDADR: 2811

WGK Germany: 3

RTECS: MP8050000

F: 10

HazardClass: 6.1(b)

PackingGroup: III

HS Code: 29419090

Toxicity: LD50 in mice (mg/kg): >1250 orally; 972.9±77 i.p. (Williams)

Use

Mycophenolic acid is a common Penicillium metabolite first reported in the 1930s as a possible mycotoxin. Re-investigation showed mycophenolic acid to display broad antitumor, antiviral, antifungal and antiprotozoan activities. Its potent immunosuppressant activity led to its commercial development to prevent kidney transplant rejection. Mycophenolic acid acts by inhibiting inosine monophosphate dehydrogenase, controlling the rate of de novo purine synthesis in proliferating B and T lymphocytes.

You can find Mycophenolic acid suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.