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ChemicalBook >> CAS DataBase List >> (5Z)-6A-CARBAPROSTAGLANDIN I2

(5Z)-6A-CARBAPROSTAGLANDIN I2

(5Z)-6A-CARBAPROSTAGLANDIN I2 price.
  • $110 - $558
  • Product name: (5Z)-6A-CARBAPROSTAGLANDIN I2
  • CAS: 69609-77-4
  • MF: C21H34O4
  • MW: 350.49
  • EINECS:
  • MDL Number:MFCD00797659
  • Synonyms:6,9ALPHA-METHYLENE-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID;(5Z)-6A-CARBAPROSTAGLANDIN I2;5-CIS CARBAPROSTACYCLIN;Pentanoic acid, 5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-1-octenyl]-2(1H)-pentalenylidene]-, (5Z)- (9CI);5 cis Carbaprostacyclin,5cis Carbaprostacyclin
4 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 500μg
  • 1mg
  • 5mg
  • ManufacturerAK Scientific
  • Product number1451AH
  • Product description5-cisCarbaprostacyclin
  • Packaging1mg
  • Price$259
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18211
  • Product description5-cis Carbaprostacyclin ≥99%
  • Packaging500μg
  • Price$110
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18211
  • Product description5-cis Carbaprostacyclin ≥99%
  • Packaging1mg
  • Price$208
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18211
  • Product description5-cis Carbaprostacyclin ≥99%
  • Packaging5mg
  • Price$558
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1451AH 5-cisCarbaprostacyclin 1mg $259 2021-12-16 Buy
Cayman Chemical 18211 5-cis Carbaprostacyclin ≥99% 500μg $110 2024-03-01 Buy
Cayman Chemical 18211 5-cis Carbaprostacyclin ≥99% 1mg $208 2024-03-01 Buy
Cayman Chemical 18211 5-cis Carbaprostacyclin ≥99% 5mg $558 2021-12-16 Buy

Properties

Boiling point :514.8±50.0 °C(Predicted)
Density :1.177±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: >10 mg/ml (from 6B-PGI2); DMSO: >5 mg/ml (from 6B-PGI2); Ethanol: >20 mg/ml (from 6B-PGI2); PBS pH 7.2: >80 μg/ml (from 6B-PGI2)
form :A crystalline solid
pka :4.77±0.10(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

5-cis Carbaprostacyclin is a stable analog of PGI2 and an isomer of carbaprostacyclin. It is a weak inhibitor of human platelet aggregation with an IC50 of 2.8 μM compared to 0.3 μM for carbaprostacyclin. 5-cis Carbaprostacyclin is a much weaker effector of rabbit mesenteric artery relaxation with an EC50 of 104 μM compared to 5.9 μM for carbaprostacyclin. It even antagonizes the adenylate cyclase activation induced by carbaprostacyclin.

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