3,3',4',5,6,7-HEXAHYDROXYFLAVONE
|
- $73 - $1238
- Product name: 3,3',4',5,6,7-HEXAHYDROXYFLAVONE
- CAS: 90-18-6
- MF: C15H10O8
- MW: 318.24
- EINECS:201-973-6
- MDL Number:MFCD00017428
- Synonyms:QUERCETAGIN;QUERCETAGENIN;QUERCETAGETIN;3,3',4',5,6,7-HEXAHYDROXYFLAVONE;3,5,6,7,3',4'-HEXAHYDROXYFLAVONE;2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4-benzopyrone ;2-(3,4-Dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-1-benzopyran-4-one;3,5,6,7-Tetrahydroxy-2-(3,4-dihydroxyphenyl)-4H-1-benzopyran-4-one
18 prices
Selected condition：
Brand
- AHH
- AK Scientific
- American Custom Chemicals Corporation
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Usbiological
Package
- 500μg
- 500ug
- 1mg
- 2mg
- 5MG
- 10mg
- 20mg
- 25mg
- 0.025g
- 1g
- ManufacturerAHH
- Product numberMT-22106
- Product descriptionQuercetagenin 98%
- Packaging0.025g
- Price$638
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8621CN
- Product descriptionQuercetagetin
- Packaging25mg
- Price$1238
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0032039
- Product descriptionQUERCETAGENIN 95.00%
- Packaging5MG
- Price$964.32
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS613852
- Product descriptionQuercetagenin 95%
- Packaging1g
- Price$681
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb594626
- Product descriptionQuercetagetin
- Packaging10mg
- Price$472.6
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb594626
- Product descriptionQuercetagetin
- Packaging20mg
- Price$612
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFQ65384
- Product descriptionQuercetagetin
- Packaging1mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFQ65384
- Product descriptionQuercetagetin
- Packaging2mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFQ65384
- Product descriptionQuercetagetin
- Packaging5mg
- Price$270
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFQ65384
- Product descriptionQuercetagetin
- Packaging10mg
- Price$440
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFQ65384
- Product descriptionQuercetagetin
- Packaging25mg
- Price$880
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18645
- Product descriptionQuercetagetin ≥98%
- Packaging500μg
- Price$73
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18645
- Product descriptionQuercetagetin ≥98%
- Packaging1mg
- Price$131
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18645
- Product descriptionQuercetagetin ≥98%
- Packaging5mg
- Price$324
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0032238
- Product descriptionQuercetagetin 99.24%
- Packaging5mg
- Price$260
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0032238
- Product descriptionQuercetagetin 99.24%
- Packaging10mg
- Price$390
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | MT-22106 | Quercetagenin 98% | 0.025g | $638 | 2021-12-16 | Buy |
| AK Scientific | 8621CN | Quercetagetin | 25mg | $1238 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0032039 | QUERCETAGENIN 95.00% | 5MG | $964.32 | 2021-12-16 | Buy |
| Arctom | AS613852 | Quercetagenin 95% | 1g | $681 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb594626 | Quercetagetin | 10mg | $472.6 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb594626 | Quercetagetin | 20mg | $612 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FQ65384 | Quercetagetin | 1mg | $85 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FQ65384 | Quercetagetin | 2mg | $135 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FQ65384 | Quercetagetin | 5mg | $270 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FQ65384 | Quercetagetin | 10mg | $440 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FQ65384 | Quercetagetin | 25mg | $880 | 2021-12-16 | Buy |
| Cayman Chemical | 18645 | Quercetagetin ≥98% | 500μg | $73 | 2024-03-01 | Buy |
| Cayman Chemical | 18645 | Quercetagetin ≥98% | 1mg | $131 | 2024-03-01 | Buy |
| Cayman Chemical | 18645 | Quercetagetin ≥98% | 5mg | $324 | 2024-03-01 | Buy |
| ChemScene | CS-0032238 | Quercetagetin 99.24% | 5mg | $260 | 2021-12-16 | Buy |
| ChemScene | CS-0032238 | Quercetagetin 99.24% | 10mg | $390 | 2021-12-16 | Buy |
Properties
Melting point :>300°C
Boiling point :732.4±60.0 °C(Predicted)
Density :1.912±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO : 125 mg/mL (392.79 mM; Need ultrasonic)
form :A crystalline solid
pka :6.12±0.40(Predicted)
LogP :2.230 (est)
Boiling point :732.4±60.0 °C(Predicted)
Density :1.912±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO : 125 mg/mL (392.79 mM; Need ultrasonic)
form :A crystalline solid
pka :6.12±0.40(Predicted)
LogP :2.230 (est)
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
The proto-oncogene serine/threonine-protein kinases, Pim-1 and Pim-2, are enzymes involved in cytokine signaling and participate in various signal transduction pathways, including cell growth, differentiation, and apoptosis. Their overexpression has been implicated in prostate cancer, some forms of leukemia, and lymphoma. Quercetagetin is a flavonol that inhibits Pim-1 with an IC50 value of 0.34 μM. It is selective for Pim-1, inhibiting Pim-2, PKA, RSK2, and JNK with IC50 values of 3.45, 21.2, 2.82, and 4.6 μM, respectively. Quercetagetin has been shown to inhibit Pim-1 activity in intact RWPE2 prostate cancer cells with an ED50 value of 5.5 μM, which led to significant growth inhibition. It can also inhibit the growth of additional prostate epithelial cell lines at a potency proportionate to their respective level of Pim-1 protein.Related product price
- Naringenin
$5-6000 - QUERCETIN-3-O-GLUCURONIDE
$49-9900 - 522-12-3
$13-800
Suppliers and manufacturers
Shanghai Zheyan Biotech Co., Ltd.
Chengdu Biopurify Phytochemicals Ltd.
Hubei Jusheng Technology Co.,Ltd.
Xi'an Kono chem co., Ltd.,
Shaanxi Pioneer Biotech Co., Ltd .
Chongqing Chemdad Co., Ltd
Neostar United (Changzhou) Industrial Co., Ltd.
Wuhan ChemNorm Biotech Co.,Ltd.
Hubei Ipure Biology Co., Ltd
