4-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)-2-((1r,4r)-4-hydroxycyclohexylamino)benzamide
- $68 - $3282.7
- Product name: 4-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)-2-((1r,4r)-4-hydroxycyclohexylamino)benzamide
- CAS: 908112-43-6
- MF: C23H27F3N4O3
- MW: 464.48
- EINECS:-0
- MDL Number:MFCD16038907
- Synonyms:PF 04928473;SNX-2112 (PF-04928473);4-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl)-2-((1r,4r)-4-hydroxycyclohexylamino)benzamide;4-(6,6-Dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)-2-((1r,4r)-4-hyd;4-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)-2-((1r,4r)-4-hydroxycyclohexylamino)benzamide;SNX-2112;SNX-2112;4-(6,6-DIMETHYL-4-OXO-3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL)-2-((1R,4R)-4-HYDROXYCYCLOHEXYLAMINO)BENZAMIDE;2-[(trans-4-Hydroxycyclohexyl)amino]-4-[4,5,6,7-tetrahydro-6,6-dimethyl-4-oxo-3-(trifluoromethyl)-1H-indazol-1-yl]benzamide
22 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 1mg
- 5MG
- 10mg
- 25mg
- 50mg
- 10mM(in 1mL DMSO)
- 100mg
- 200mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product numberX7588
- Product description4-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)-2-(((1r,4r)-4-hydroxycyclohexyl)amino)benzamide
- Packaging100mg
- Price$1717
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0014149
- Product descriptionSNX-2112 95.00%
- Packaging5MG
- Price$459.8
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4068
- Product descriptionSNX-2112
- Packaging5mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4068
- Product descriptionSNX-2112
- Packaging10mg
- Price$260
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4068
- Product descriptionSNX-2112
- Packaging10mM(in 1mL DMSO)
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4068
- Product descriptionSNX-2112
- Packaging50mg
- Price$680
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4068
- Product descriptionSNX-2112
- Packaging100mg
- Price$980
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146264
- Product descriptionSNX-2112 (PF-04928473) >98%
- Packaging100mg
- Price$838.1
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146264
- Product descriptionSNX-2112 (PF-04928473) >98%
- Packaging250mg
- Price$1504.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146264
- Product descriptionSNX-2112 (PF-04928473) >98%
- Packaging1g
- Price$3282.7
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFS103989
- Product descriptionSNX 2112
- Packaging10mg
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFS103989
- Product descriptionSNX 2112
- Packaging50mg
- Price$787.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number22359
- Product descriptionSNX-2112 ≥98%
- Packaging1mg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22359
- Product descriptionSNX-2112 ≥98%
- Packaging5mg
- Price$268
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22359
- Product descriptionSNX-2112 ≥98%
- Packaging10mg
- Price$401
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22359
- Product descriptionSNX-2112 ≥98%
- Packaging25mg
- Price$917
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | X7588 | 4-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)-2-(((1r,4r)-4-hydroxycyclohexyl)amino)benzamide | 100mg | $1717 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0014149 | SNX-2112 95.00% | 5MG | $459.8 | 2021-12-16 | Buy |
ApexBio Technology | A4068 | SNX-2112 | 5mg | $190 | 2021-12-16 | Buy |
ApexBio Technology | A4068 | SNX-2112 | 10mg | $260 | 2021-12-16 | Buy |
ApexBio Technology | A4068 | SNX-2112 | 10mM(in 1mL DMSO) | $280 | 2021-12-16 | Buy |
ApexBio Technology | A4068 | SNX-2112 | 50mg | $680 | 2021-12-16 | Buy |
ApexBio Technology | A4068 | SNX-2112 | 100mg | $980 | 2021-12-16 | Buy |
Biorbyt Ltd | orb146264 | SNX-2112 (PF-04928473) >98% | 100mg | $838.1 | 2021-12-16 | Buy |
Biorbyt Ltd | orb146264 | SNX-2112 (PF-04928473) >98% | 250mg | $1504.5 | 2021-12-16 | Buy |
Biorbyt Ltd | orb146264 | SNX-2112 (PF-04928473) >98% | 1g | $3282.7 | 2021-12-16 | Buy |
Biosynth Carbosynth | FS103989 | SNX 2112 | 10mg | $225 | 2021-12-16 | Buy |
Biosynth Carbosynth | FS103989 | SNX 2112 | 50mg | $787.5 | 2021-12-16 | Buy |
Cayman Chemical | 22359 | SNX-2112 ≥98% | 1mg | $68 | 2024-03-01 | Buy |
Cayman Chemical | 22359 | SNX-2112 ≥98% | 5mg | $268 | 2024-03-01 | Buy |
Cayman Chemical | 22359 | SNX-2112 ≥98% | 10mg | $401 | 2024-03-01 | Buy |
Cayman Chemical | 22359 | SNX-2112 ≥98% | 25mg | $917 | 2024-03-01 | Buy |
Properties
Melting point :265-266℃
Boiling point :619.8±55.0 °C(Predicted)
Density :1.47
storage temp. :Store at -20°C
solubility :≥23.05 mg/mL in DMSO; insoluble in H2O; ≥9.6 mg/mL in EtOH with gentle warming and ultrasonic
form :solid
pka :15.07±0.50(Predicted)
Boiling point :619.8±55.0 °C(Predicted)
Density :1.47
storage temp. :Store at -20°C
solubility :≥23.05 mg/mL in DMSO; insoluble in H2O; ≥9.6 mg/mL in EtOH with gentle warming and ultrasonic
form :solid
pka :15.07±0.50(Predicted)
Safety Information
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Signal word: | Warning | ||||||||||||||
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Description
SNX-2112 is a selective heat shock protein 90 (Hsp90) inhibitor which can exert a potent anticancer activity. Studies demonstates that SNX-2112 can exhibit a potent anticancer activity against B16 melanoma cells both in vitro and in vivo, by inhibiting cell proliferation and inducing cell cycle arrest and apoptosis in a mechanism dependent on the degredation of Hsp90 client proteins.More related product prices
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