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ChemicalBook >> CAS DataBase List >> Cdk1 Inhibitor

Cdk1 Inhibitor

Cdk1 Inhibitor price.
  • $40 - $168
  • Product name: Cdk1 Inhibitor
  • CAS: 220749-41-7
  • MF: C17H11ClN2O
  • MW: 294.73
  • EINECS:
  • MDL Number:
  • Synonyms:Cdk1 Inhibitor;Cdk1 Inhbitor;CDK1-IN-2;2H-Indol-2-one, 3-[(2-chloro-1H-indol-3-yl)methylene]-1,3-dihydro-;3-((2-Chloro-1H-indol-3-yl)methylene)indolin-2-one
2 prices
Selected condition:
Brand
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • ManufacturerCayman Chemical
  • Product number21501
  • Product descriptionCdk1 Inhbitor
  • Packaging1mg
  • Price$40
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21501
  • Product descriptionCdk1 Inhbitor
  • Packaging5mg
  • Price$168
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 21501 Cdk1 Inhbitor 1mg $40 2024-03-01 Buy
Cayman Chemical 21501 Cdk1 Inhbitor 5mg $168 2024-03-01 Buy

Properties

Boiling point :585.1±50.0 °C(Predicted)
Density :1.450±0.06 g/cm3(Predicted)
solubility :DMSO: soluble
form :A solid
pka :11.94±0.20(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Cdk1 Inhibitor is an indolylmethylene-2-indolinone derivative that exhibits potent anti-proliferative properties (IC50 = 2 M HeLa cells). Cdk1 Inhibitor acts as a selective and ATP-competitive inhibitor of Cdk1/cyclin B (IC50 = 5.8 M). Also inhibits Cdk5 with a IC50 = 25 M. Binds to the ATP pocket on the Cdk1 active site. Does not affect the activity of GSK-3b even at 100 M concentrations.