Welcome to chemicalbook!
400-158-6606
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook >> CAS DataBase List >> Gimeracil

Gimeracil

Gimeracil price.
  • $5 - $1686.3
  • Product name: Gimeracil
  • CAS: 103766-25-2
  • MF: C5H4ClNO2
  • MW: 145.54
  • EINECS:1312995-182-4
  • MDL Number:MFCD08458352
  • Synonyms:GIMERACIL;gimestat;5-Chloro-2,4-dihydroxypyridine;5-Chloro-4-hydroxy-2(1H)-pyridinone;5-Chloro-4-hydroxy-2-pyridone;2(1H)-Pyridinone,5-chloro-4-hydroxy-(9CI);5-chloropyridine-2,4-diol;2(1H)-Pyridinone, 5-chloro-4-hydroxy-
47 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Cayman Chemical
  • Chem-Impex
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Labseeker
  • Sigma-Aldrich
  • TCI Chemical
  • Usbiological
Package
  • 10μg
  • 5mg
  • 10mg
  • 25MG
  • 50mg
  • 100mg
  • 250MG
  • 0.25G
  • 500mg
  • 10mM(in 1mL DMSO)
  • 1g
  • 5g
  • 10g
  • 25g
  • 100g
  • 48Tests
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-G0209-G001
  • Product descriptionGimeracil ≥99%
  • Packaging1g
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberH836
  • Product descriptionGimeracil
  • Packaging100g
  • Price$427
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA230901
  • Product descriptionGimeracil 98+%
  • Packaging100mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA230901
  • Product descriptionGimeracil 98+%
  • Packaging1g
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA230901
  • Product descriptionGimeracil 98+%
  • Packaging5g
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA230901
  • Product descriptionGimeracil 98+%
  • Packaging10g
  • Price$21
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA230901
  • Product descriptionGimeracil 98+%
  • Packaging25g
  • Price$38
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA230901
  • Product descriptionGimeracil 98+%
  • Packaging100g
  • Price$148
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002826
  • Product descriptionGIMERACIL 95.00%
  • Packaging0.25G
  • Price$269
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002826
  • Product descriptionGIMERACIL 95.00%
  • Packaging25MG
  • Price$716.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002826
  • Product descriptionGIMERACIL 95.00%
  • Packaging250MG
  • Price$1686.3
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4342
  • Product descriptionGimeracil
  • Packaging25mg
  • Price$58
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4342
  • Product descriptionGimeracil
  • Packaging10mM(in 1mL DMSO)
  • Price$61
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR940679
  • Product description5-Chloro-2,4-dihydroxypyridine 95%
  • Packaging5g
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR940679
  • Product description5-Chloro-2,4-dihydroxypyridine 95%
  • Packaging25g
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR940679
  • Product description5-Chloro-2,4-dihydroxypyridine 95%
  • Packaging100g
  • Price$520
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-G0209-G001 Gimeracil ≥99% 1g $59 2021-12-16 Buy
AK Scientific H836 Gimeracil 100g $427 2021-12-16 Buy
Ambeed A230901 Gimeracil 98+% 100mg $5 2021-12-16 Buy
Ambeed A230901 Gimeracil 98+% 1g $6 2021-12-16 Buy
Ambeed A230901 Gimeracil 98+% 5g $11 2021-12-16 Buy
Ambeed A230901 Gimeracil 98+% 10g $21 2021-12-16 Buy
Ambeed A230901 Gimeracil 98+% 25g $38 2021-12-16 Buy
Ambeed A230901 Gimeracil 98+% 100g $148 2021-12-16 Buy
American Custom Chemicals Corporation API0002826 GIMERACIL 95.00% 0.25G $269 2021-12-16 Buy
American Custom Chemicals Corporation API0002826 GIMERACIL 95.00% 25MG $716.1 2021-12-16 Buy
American Custom Chemicals Corporation API0002826 GIMERACIL 95.00% 250MG $1686.3 2021-12-16 Buy
ApexBio Technology A4342 Gimeracil 25mg $58 2021-12-16 Buy
ApexBio Technology A4342 Gimeracil 10mM(in 1mL DMSO) $61 2021-12-16 Buy
Apolloscientific OR940679 5-Chloro-2,4-dihydroxypyridine 95% 5g $90 2021-12-16 Buy
Apolloscientific OR940679 5-Chloro-2,4-dihydroxypyridine 95% 25g $150 2021-12-16 Buy
Apolloscientific OR940679 5-Chloro-2,4-dihydroxypyridine 95% 100g $520 2021-12-16 Buy

Properties

Melting point :274 °C
Boiling point :255.1±40.0 °C(Predicted)
Density :1.56±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 5 mg/ml).
form :solid
pka :4.50±1.00(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :ZPLQIPFOCGIIHV-UHFFFAOYSA-N
CAS DataBase Reference :103766-25-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501 Dispose of contents/container to..…

Description

5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine, which is required for DNA synthesis. It has been widely used to treat many gastrointestinal tract adenocarcinomas with mixed clinical efficacy. Gimeracil is an inhibitor of dihydropyrimidine dehydrogenase, the rate limiting enzyme for the catabolism of pyrimidines, including 5-fluorouracil. It has been administered concomitantly with 5-fluorouracil in a chemotherapy regimen termed S-1 to block 5-fluorouracil degradation, thus prolonging circulating 5-fluorouracil concentrations. Furthermore, at 1 mM gimeracil has been shown to inhibit homologous recombination in the repair of DNA double strand breaks, which can sensitize cancer cells to radiotherapy.

Related product price