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ChemicalBook >> CAS DataBase List >> IC 261

IC 261

$15 - $1450
Product name: IC 261
CAS: 186611-52-9
MF: C18H17NO4
MW: 311.335
EINECS:
MDL Number:MFCD00118156
Synonyms:SU5607, 1,3-Dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one;1,3-Dihydro-3-[(2,4,6-triMethoxyphenyl)Methylene]-2H-indol-2-one, SU5607;SU-5607 IC 261;(E)-3-(2,4,6-trimethoxybenzylidene)indolin-2-one;IC261, >98%;IC-261(SU-5607);IC261 - CAS 186611-52-9 - Calbiochem;IC261;SU5607;IC 261;SU 5607

Price40 Properties Safety Information Description

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Brand

Ambeed
ApexBio Technology
Arctom
Cayman Chemical
Chemenu
ChemScene
Crysdot
CSNpharm
DC Chemicals
Sigma-Aldrich
TCI Chemical

Package

1mg
5mg
10mg
25mg
50mg
100mg
250mg
1g

ManufacturerAmbeed
Product numberA267194
Product descriptionIC 261 98+%
Packaging1mg
Price$15
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA267194
Product descriptionIC 261 98+%
Packaging5mg
Price$20
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA267194
Product descriptionIC 261 98+%
Packaging10mg
Price$27
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA267194
Product descriptionIC 261 98+%
Packaging25mg
Price$35
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA267194
Product descriptionIC 261 98+%
Packaging50mg
Price$45
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA267194
Product descriptionIC 261 98+%
Packaging100mg
Price$86
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA267194
Product descriptionIC 261 98+%
Packaging250mg
Price$129
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA267194
Product descriptionIC 261 98+%
Packaging1g
Price$328
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB6108
Product descriptionIC 261
Packaging5mg
Price$90
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB6108
Product descriptionIC 261
Packaging10mg
Price$160
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB6108
Product descriptionIC 261
Packaging50mg
Price$680
Updated2021-12-16
Buy

ManufacturerArctom
Product numberAS033319
Product descriptionIC 261 ≥98%
Packaging1mg
Price$15
Updated2021-12-16
Buy

ManufacturerArctom
Product numberAS033319
Product descriptionIC 261 ≥98%
Packaging5mg
Price$20
Updated2021-12-16
Buy

ManufacturerArctom
Product numberAS033319
Product descriptionIC 261 ≥98%
Packaging10mg
Price$27
Updated2021-12-16
Buy

ManufacturerArctom
Product numberAS033319
Product descriptionIC 261 ≥98%
Packaging25mg
Price$35
Updated2021-12-16
Buy

ManufacturerArctom
Product numberAS033319
Product descriptionIC 261 ≥98%
Packaging50mg
Price$45
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
Ambeed	A267194	IC 261 98+%	1mg	$15	2021-12-16	Buy
Ambeed	A267194	IC 261 98+%	5mg	$20	2021-12-16	Buy
Ambeed	A267194	IC 261 98+%	10mg	$27	2021-12-16	Buy
Ambeed	A267194	IC 261 98+%	25mg	$35	2021-12-16	Buy
Ambeed	A267194	IC 261 98+%	50mg	$45	2021-12-16	Buy
Ambeed	A267194	IC 261 98+%	100mg	$86	2021-12-16	Buy
Ambeed	A267194	IC 261 98+%	250mg	$129	2021-12-16	Buy
Ambeed	A267194	IC 261 98+%	1g	$328	2021-12-16	Buy
ApexBio Technology	B6108	IC 261	5mg	$90	2021-12-16	Buy
ApexBio Technology	B6108	IC 261	10mg	$160	2021-12-16	Buy
ApexBio Technology	B6108	IC 261	50mg	$680	2021-12-16	Buy
Arctom	AS033319	IC 261 ≥98%	1mg	$15	2021-12-16	Buy
Arctom	AS033319	IC 261 ≥98%	5mg	$20	2021-12-16	Buy
Arctom	AS033319	IC 261 ≥98%	10mg	$27	2021-12-16	Buy
Arctom	AS033319	IC 261 ≥98%	25mg	$35	2021-12-16	Buy
Arctom	AS033319	IC 261 ≥98%	50mg	$45	2021-12-16	Buy

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Properties

Melting point :214 °C
storage temp. :protect from light
solubility :DMSO: 18 mg/mL soluble
form :solid
color :yellow

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

IC261 is a reversible, ATP-competitive inhibitor of casein kinase 1 (CK1) that inhibits CK1δ and CK1? (IC50 = ~1 μM for both), as well as CK1α (IC50 = 16 μM). It is at least 100-fold less effective against PKA, p34cdc2, and p55fyn. IC 261, at 1 μM, inhibits cytokinesis in primary mouse embryo fibroblasts. IC261 is used to elucidate the role of CK1 in cells and in whole organisms.

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