Lopinavir-d8
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- $456 - $2080
- Product name: Lopinavir-d8
- CAS: 1322625-54-6
- MF: C37H40D8N4O5
- MW: 636.850114224
- EINECS:
- MDL Number:
- Synonyms:LOPINAVIR-D8;2,3,4,4,4-pentadeuterio-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-2-(2-oxo-1,3-diazinan-1-yl)-3-(trideuteriomethyl)butanamide
4 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- TRC
- Usbiological
Package
- 1mg
- 10mg
- ManufacturerAK Scientific
- Product number5704DV
- Product description2,3,4,4,4-Pentadeuterio-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-2-(2-oxo-1,3-diazinan-1-yl)-3-(trideuteriomethyl)butanamide
- Packaging1mg
- Price$606
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number25284
- Product descriptionLopinavir-d8 ≥99% deuterated forms (d1-d8)
- Packaging1mg
- Price$456
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberL469482
- Product descriptionLopinavir-d8
- Packaging10mg
- Price$2080
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product numberL3420-31
- Product descriptionLopinavir-d8
- Packaging1mg
- Price$566
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 5704DV | 2,3,4,4,4-Pentadeuterio-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-2-(2-oxo-1,3-diazinan-1-yl)-3-(trideuteriomethyl)butanamide | 1mg | $606 | 2021-12-16 | Buy |
| Cayman Chemical | 25284 | Lopinavir-d8 ≥99% deuterated forms (d1-d8) | 1mg | $456 | 2024-03-01 | Buy |
| TRC | L469482 | Lopinavir-d8 | 10mg | $2080 | 2021-12-16 | Buy |
| Usbiological | L3420-31 | Lopinavir-d8 | 1mg | $566 | 2021-12-16 | Buy |
Properties
Melting point :>96°C (dec.)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
color :Off-White to Pale Beige
Stability :Hygroscopic
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
color :Off-White to Pale Beige
Stability :Hygroscopic
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||||
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Description
Lopinavir-d8 is intended for use as an internal standard for the quantification of lopinavir by GC- or LC-MS. Lopinavir is a potent HIV-1 protease inhibitor (Ki = 1.3 pM for wild-type enzyme). It inhibits the replication of clinical isolates of HIV-1 (EC50s = 5-52 nM). Lopinavir reduces the infectious virus yield and viral RNA copy numbers in the culture supernatant of Vero E6 cells infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; EC50s = 26.63 and 26.10 μM, respectively). It reduces lung and kidney viral load, bronchointerstitial pneumonia, and pulmonary inflammatory cell infiltration in a marmoset model of Middle East respiratory syndrome coronavirus (MERS-CoV) infection when administered in combination with ritonavir .Suppliers and manufacturers
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