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ChemicalBook >> CAS DataBase List >> Niclosamide

Niclosamide

Niclosamide price.
  • $14 - $796.77
  • Product name: Niclosamide
  • CAS: 50-65-7
  • MF: C13H8Cl2N2O4
  • MW: 327.12
  • EINECS:200-056-8
  • MDL Number:MFCD00057597
  • Synonyms:Nc osamide;NICLOSAMID PESTANAL 250 MG;NICLOSAMID PESTANAL;2-CHLORO-4-NITROHENYLAMIDE-6-CHLOROSALICYLIC ACID;Niclosamide 1420-04-8,;5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza;Niclosamide (base and/or unspecified salts);5-CHLORO-N-(2-CHLORO-5-NITROPHENYL)-2-HYDROXYBENZAMIDE
24 prices
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  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
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  • 5g
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  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3643-M100
  • Product descriptionNiclosamide ≥95%
  • Packaging100mg
  • Price$35
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1745
  • Product descriptionNiclosamide 98%
  • Packaging1000g
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberI012
  • Product descriptionNiclosamide
  • Packaging5g
  • Price$14
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003561
  • Product descriptionNiclosamide 95.00%
  • Packaging1G
  • Price$619.7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003561
  • Product descriptionNiclosamide 95.00%
  • Packaging2.5G
  • Price$796.77
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2283
  • Product descriptionNiclosamide
  • Packaging10g
  • Price$76
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60348
  • Product descriptionNiclosamide ≥98%
  • Packaging20mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10649
  • Product descriptionNiclosamide ≥95%
  • Packaging25g
  • Price$49
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10649
  • Product descriptionNiclosamide ≥95%
  • Packaging50g
  • Price$92
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10649
  • Product descriptionNiclosamide ≥95%
  • Packaging100g
  • Price$172
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10649
  • Product descriptionNiclosamide ≥95%
  • Packaging250g
  • Price$356
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2618
  • Product descriptionNiclosamide 98.68%
  • Packaging500mg
  • Price$50
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-2618
  • Product descriptionNiclosamide 98.68%
  • Packaging5g
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2618
  • Product descriptionNiclosamide 98.68%
  • Packaging10g
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31001717
  • Product descriptionNiclosamide 97+%
  • Packaging100g
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31001717
  • Product descriptionNiclosamide 97+%
  • Packaging500g
  • Price$178
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3643-M100 Niclosamide ≥95% 100mg $35 2021-12-16 Buy
AHH API-1745 Niclosamide 98% 1000g $130 2021-12-16 Buy
AK Scientific I012 Niclosamide 5g $14 2021-12-16 Buy
American Custom Chemicals Corporation API0003561 Niclosamide 95.00% 1G $619.7 2021-12-16 Buy
American Custom Chemicals Corporation API0003561 Niclosamide 95.00% 2.5G $796.77 2021-12-16 Buy
ApexBio Technology B2283 Niclosamide 10g $76 2021-12-16 Buy
Arctom CFN60348 Niclosamide ≥98% 20mg $30 2021-12-16 Buy
Cayman Chemical 10649 Niclosamide ≥95% 25g $49 2024-03-01 Buy
Cayman Chemical 10649 Niclosamide ≥95% 50g $92 2024-03-01 Buy
Cayman Chemical 10649 Niclosamide ≥95% 100g $172 2024-03-01 Buy
Cayman Chemical 10649 Niclosamide ≥95% 250g $356 2024-03-01 Buy
ChemScene CS-2618 Niclosamide 98.68% 500mg $50 2021-12-16 Buy
ChemScene CS-2618 Niclosamide 98.68% 5g $60 2021-12-16 Buy
ChemScene CS-2618 Niclosamide 98.68% 10g $96 2021-12-16 Buy
Crysdot CD31001717 Niclosamide 97+% 100g $59 2021-12-16 Buy
Crysdot CD31001717 Niclosamide 97+% 500g $178 2021-12-16 Buy

Properties

Melting point :225-230°
Boiling point :424.5±45.0 °C(Predicted)
Density :1.6646 (rough estimate)
refractive index :1.6200 (estimate)
storage temp. :Sealed in dry,Room Temperature
solubility :acetone: methanol: soluble50mg/mL (methanol:acetone (1:1))
form :Pale yellow solid
pka :7.45±0.43(Predicted)
color :Yellow
Water Solubility :13.32mg/L(25 ºC)
BRN :2820605
BCS Class :4
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :RJMUSRYZPJIFPJ-UHFFFAOYSA-N
CAS DataBase Reference :50-65-7(CAS DataBase Reference)
EPA Substance Registry System :Niclosamide (50-65-7)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.
P391 Collect spillage. Hazardous to the aquatic environment
P501 Dispose of contents/container to..…

Description

Niclosamide is a salicylanilide compound with antihelminthic actions. It specifically inhibits the signal transducer and activator of transcription 3 (STAT3) with an IC50 value of 0.25 μM. It does not decrease the level or activity of the related STAT1, STAT5, JAK, or Src kinases. Through its effects on STAT3, niclosamide inhibits the proliferation and colony formation of Du145 prostate cancer cells, which have constitutively active STAT3, with IC50 values of 0.7 and 0.1 μM, respectively.

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