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ChemicalBook >> CAS DataBase List >> PUROMYCIN DIHYDROCHLORIDE

PUROMYCIN DIHYDROCHLORIDE

PUROMYCIN DIHYDROCHLORIDE price.
  • $11 - $5076
  • Product name: PUROMYCIN DIHYDROCHLORIDE
  • CAS: 58-58-2
  • MF: C22H30ClN7O5
  • MW: 507.98
  • EINECS:200-387-8
  • MDL Number:MFCD00012691
  • Synonyms:Puromycin dihydrochloride hydrate,99%;3’-(alpha-amino-p-methoxyhydrocinnamamido)-3’-deoxy-n,n-dimethyl-adenosin ;adenosine,3’-((2-amino-3-(4-methoxyphenyl)-1-oxopropyl)amino)-3’-deoxy-n,n-dim ;dihydrochloride,(s)-ethyl ;PUROMYCIN Dihydrochloride Dihydrate 96%;3'-[[12-AMINO-3-(4-METHOXYPHENYL)-1-OXOPROPYL]AMINO]-3'-DEOXY-N,N-DIMETHYL-ADENOSINE 2HCL;3'-[[2-AMINO-3-(4-METHOXYPHENYL)-1-OXOPROPYL]AMINO]-3'-DEOXY-N,N-DIMETHYLADENOSINE DIHYDROCHLORIDE;3'-[[2-AMINO-3-(4-METHOXYPHENYL)-1-OXOPROPYL]AMINO]-3'-DEOXY-N,N-DIMETHYL-ADENOSINE 2HCL
46 prices
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Brand
  • Adipogen Life Sciences
  • Alfa Aesar
  • Ambeed
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • Iris Biotech GmbH
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
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  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0078-M100
  • Product descriptionPuromycin dihydrochloride ≥98%(HPLC)
  • Packaging100mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61278
  • Product descriptionPuromycin dihydrochloride, 99%
  • Packaging25mg
  • Price$81.8
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61278
  • Product descriptionPuromycin dihydrochloride, 99%
  • Packaging100mg
  • Price$293
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61278
  • Product descriptionPuromycin dihydrochloride, 99%
  • Packaging500mg
  • Price$823
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA547954
  • Product description(S)-2-Amino-N-((2S,3S,4R,5R)-5-(6-(Dimethylamino)-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)-3-(4-methoxyphenyl)propanamidedihydrochloride 98%
  • Packaging1mg
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA547954
  • Product description(S)-2-Amino-N-((2S,3S,4R,5R)-5-(6-(Dimethylamino)-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)-3-(4-methoxyphenyl)propanamidedihydrochloride 98%
  • Packaging5mg
  • Price$24
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA547954
  • Product description(S)-2-Amino-N-((2S,3S,4R,5R)-5-(6-(Dimethylamino)-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)-3-(4-methoxyphenyl)propanamidedihydrochloride 98%
  • Packaging10mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA547954
  • Product description(S)-2-Amino-N-((2S,3S,4R,5R)-5-(6-(Dimethylamino)-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)-3-(4-methoxyphenyl)propanamidedihydrochloride 98%
  • Packaging50mg
  • Price$128
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7587
  • Product descriptionPuromycin dihydrochloride
  • Packaging50mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIP4033
  • Product descriptionPuromycindihydrochloride(animalfree)
  • Packaging25mg
  • Price$73
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIP4033
  • Product descriptionPuromycindihydrochloride(animalfree)
  • Packaging50mg
  • Price$131
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIP4033
  • Product descriptionPuromycindihydrochloride(animalfree)
  • Packaging100mg
  • Price$232
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60357
  • Product descriptionPuromycin2HCl ≥98%
  • Packaging20mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13884
  • Product descriptionPuromycin (hydrochloride) ≥98%
  • Packaging25mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13884
  • Product descriptionPuromycin (hydrochloride) ≥98%
  • Packaging50mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13884
  • Product descriptionPuromycin (hydrochloride) ≥98%
  • Packaging100mg
  • Price$109
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CN2-0078-M100 Puromycin dihydrochloride ≥98%(HPLC) 100mg $90 2021-12-16 Buy
Alfa Aesar J61278 Puromycin dihydrochloride, 99% 25mg $81.8 2024-03-01 Buy
Alfa Aesar J61278 Puromycin dihydrochloride, 99% 100mg $293 2024-03-01 Buy
Alfa Aesar J61278 Puromycin dihydrochloride, 99% 500mg $823 2024-03-01 Buy
Ambeed A547954 (S)-2-Amino-N-((2S,3S,4R,5R)-5-(6-(Dimethylamino)-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)-3-(4-methoxyphenyl)propanamidedihydrochloride 98% 1mg $11 2021-12-16 Buy
Ambeed A547954 (S)-2-Amino-N-((2S,3S,4R,5R)-5-(6-(Dimethylamino)-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)-3-(4-methoxyphenyl)propanamidedihydrochloride 98% 5mg $24 2021-12-16 Buy
Ambeed A547954 (S)-2-Amino-N-((2S,3S,4R,5R)-5-(6-(Dimethylamino)-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)-3-(4-methoxyphenyl)propanamidedihydrochloride 98% 10mg $45 2021-12-16 Buy
Ambeed A547954 (S)-2-Amino-N-((2S,3S,4R,5R)-5-(6-(Dimethylamino)-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)-3-(4-methoxyphenyl)propanamidedihydrochloride 98% 50mg $128 2021-12-16 Buy
ApexBio Technology B7587 Puromycin dihydrochloride 50mg $140 2021-12-16 Buy
Apolloscientific BIP4033 Puromycindihydrochloride(animalfree) 25mg $73 2021-12-16 Buy
Apolloscientific BIP4033 Puromycindihydrochloride(animalfree) 50mg $131 2021-12-16 Buy
Apolloscientific BIP4033 Puromycindihydrochloride(animalfree) 100mg $232 2021-12-16 Buy
Arctom CFN60357 Puromycin2HCl ≥98% 20mg $70 2021-12-16 Buy
Cayman Chemical 13884 Puromycin (hydrochloride) ≥98% 25mg $37 2024-03-01 Buy
Cayman Chemical 13884 Puromycin (hydrochloride) ≥98% 50mg $62 2024-03-01 Buy
Cayman Chemical 13884 Puromycin (hydrochloride) ≥98% 100mg $109 2024-03-01 Buy

Properties

Melting point :168-170℃
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :H2O: soluble50mg/mL (Sterilize stock solution by filtration using 0.22 μm filter then store in aliquots at 20 °C.)
form :solution
color :yellow-white
Water Solubility :Soluble in water
Merck :14,7943
BRN :3853613
Stability :Stable. Heat sensitive. Incompatible with strong oxidizing agents.
InChIKey :MKSVFGKWZLUTTO-NGOAXYITSA-N
EPA Substance Registry System :Adenosine, 3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-, dihydrochloride (58-58-2)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Puromycin is an aminonucleoside antibiotic, derived from S. alboniger, that blocks protein synthesis in both prokaryotes and eukaryotes by causing premature termination of nascent polypeptide chains. A portion of the puromycin molecule resembles the 3' end of aminoacylated tRNA. It enters the A site of the ribosome and attaches to the growing polypeptide chain at the peptidyl-transferase center, causing the formation of a puromycylated nascent chain and premature chain release. The 3' position contains an amide linkage instead of the normal ester linkage of tRNA, making it much more resistant to hydrolysis and halting the activity of the ribosome. These properties of puromycin have been exploited in assays for peptide-bond formation and elongation and also the antibiotic is often used as selective agent in cell culture systems.

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