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ChemicalBook >> CAS DataBase List >> S0859

S0859

S0859 price.
  • $32 - $6476
  • Product name: S0859
  • CAS: 1019331-10-2
  • MF: C29H24ClN3O3S
  • MW: 530.04
  • EINECS:-0
  • MDL Number:MFCD23136018
  • Synonyms:2-chloro-N-[[2'-[(cyanoamino)sulfonyl][1,1'-biphenyl]-4-yl]methyl]-N-[(4-methylphenyl)methyl]- S0859;2-Chloro-N-[[2′-[(cyanoamino)sulfonyl][1,1′-biphenyl]-4-yl]methyl]-N-[(4-methylphenyl)methyl]-benzamide;2-Chloro-N-((2'-(N-cyanosulfamoyl)-[1,1'-biphenyl]-4-yl)methyl)-N-(4-methylbenzyl)benzamide;S0859;(4S)-4-HYDROXY-4-[(3R)-3-HYDROXYBUTYL]-3,5,5-TRIMETHYL-2-CYCLOHEXEN-1-ONE;100852;S 0859; S-0859; S 0859; S-0859;CS-1766
23 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1g
  • 5g
  • ManufacturerAK Scientific
  • Product numberSYN5105
  • Product descriptionS0859
  • Packaging100mg
  • Price$860
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3783
  • Product descriptionS0859
  • Packaging5mg
  • Price$104
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3783
  • Product descriptionS0859
  • Packaging10mg
  • Price$173
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3783
  • Product descriptionS0859
  • Packaging50mg
  • Price$693
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18497
  • Product descriptionS0859 ≥95%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18497
  • Product descriptionS0859 ≥95%
  • Packaging5mg
  • Price$86
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18497
  • Product descriptionS0859 ≥95%
  • Packaging10mg
  • Price$153
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18497
  • Product descriptionS0859 ≥95%
  • Packaging25mg
  • Price$343
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1092
  • Product descriptionS0859 99.78%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1092
  • Product descriptionS0859 99.78%
  • Packaging10mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1092
  • Product descriptionS0859 99.78%
  • Packaging50mg
  • Price$390
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004831
  • Product descriptionS0859 98+%
  • Packaging5mg
  • Price$54
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004831
  • Product descriptionS0859 98+%
  • Packaging10mg
  • Price$92
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004831
  • Product descriptionS0859 98+%
  • Packaging50mg
  • Price$370
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7882
  • Product descriptionS0859 >98%
  • Packaging100mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7882
  • Product descriptionS0859 >98%
  • Packaging1g
  • Price$1500
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5105 S0859 100mg $860 2021-12-16 Buy
ApexBio Technology A3783 S0859 5mg $104 2021-12-16 Buy
ApexBio Technology A3783 S0859 10mg $173 2021-12-16 Buy
ApexBio Technology A3783 S0859 50mg $693 2021-12-16 Buy
Cayman Chemical 18497 S0859 ≥95% 1mg $32 2024-03-01 Buy
Cayman Chemical 18497 S0859 ≥95% 5mg $86 2024-03-01 Buy
Cayman Chemical 18497 S0859 ≥95% 10mg $153 2024-03-01 Buy
Cayman Chemical 18497 S0859 ≥95% 25mg $343 2024-03-01 Buy
ChemScene CS-1092 S0859 99.78% 5mg $60 2021-12-16 Buy
ChemScene CS-1092 S0859 99.78% 10mg $100 2021-12-16 Buy
ChemScene CS-1092 S0859 99.78% 50mg $390 2021-12-16 Buy
Crysdot CD31004831 S0859 98+% 5mg $54 2021-12-16 Buy
Crysdot CD31004831 S0859 98+% 10mg $92 2021-12-16 Buy
Crysdot CD31004831 S0859 98+% 50mg $370 2021-12-16 Buy
DC Chemicals DC7882 S0859 >98% 100mg $400 2021-12-16 Buy
DC Chemicals DC7882 S0859 >98% 1g $1500 2021-12-16 Buy

Properties

Boiling point :748.5±70.0 °C(Predicted)
Density :1.313±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
pka :-1.34±0.40(Predicted)
color :white to light brown

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

S0859 is an N-cyanosulphonamide that blocks the sodium/bicarbonate cotransporter (NBC, also known as SLC4A7), which regulates intracellular pH, particularly in myocytes. It inhibits intracellular pH recovery in myocytes with a Ki value of 1.7 μM, with full inhibition occurring at ~30 μM. S0859 does not affect other exchange proteins or enzymes that might regulate intracellular pH. It prevents changes in pH associated with depolarization and hyperpolarization of ventricular myocytes from rabbit, rat, and guinea pig. S0859 has also been used to study the role of NBC in coronary endothelial cells, cancer cells, embryonic kidney cells, and neutrophils.