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ChemicalBook >> CAS DataBase List >> SIMVASTATIN, SODIUM SALT

SIMVASTATIN, SODIUM SALT

SIMVASTATIN, SODIUM SALT price.
  • $36 - $732
  • Product name: SIMVASTATIN, SODIUM SALT
  • CAS: 101314-97-0
  • MF: C25H41NaO6
  • MW: 460.59
  • EINECS:
  • MDL Number:MFCD04974206
  • Synonyms:SIMVASTATIN HYDROXY ACID SODIUM SALT;SIMVASTATIN, SODIUM SALT;IMp. A (EP) as SodiuM Salt: (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-DiMethylbutanoyl)oxy]-2,6-diMethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic Acid SodiuM Salt (Tenivastatin SodiuM Salt;Simvastatin Impurity as Sodium Salt;Simvastati;SiMvastatin IMp. A (EP) as SodiuM Salt;sodium,(3R,5S)-7-[(1R,2R,6S,8S)-8-(2,2-dimethylbutanoyloxy)-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate;Simvastatin hydroxyl acid sodium salt-d6
11 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • ApexBio Technology
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0539-M025
  • Product descriptionSimvastatin.sodiumsalt ≥98%(HPLC)
  • Packaging25mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4426
  • Product descriptionSimvastatin(sodiumsalt)
  • Packaging25mg
  • Price$146
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4426
  • Product descriptionSimvastatin(sodiumsalt)
  • Packaging100mg
  • Price$341
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS010751
  • Product descriptionSimvastatinsodiumsalt 95%
  • Packaging1g
  • Price$732
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFS65168
  • Product descriptionSimvastatin Na
  • Packaging10mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFS65168
  • Product descriptionSimvastatin Na
  • Packaging50mg
  • Price$158
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010345
  • Product descriptionSimvastatin (sodium salt) ≥98%
  • Packaging1mg
  • Price$36
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010345
  • Product descriptionSimvastatin (sodium salt) ≥98%
  • Packaging5mg
  • Price$155
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010345
  • Product descriptionSimvastatin (sodium salt) ≥98%
  • Packaging10mg
  • Price$274
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010345
  • Product descriptionSimvastatin (sodium salt) ≥98%
  • Packaging25mg
  • Price$595
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberS485050
  • Product descriptionSimvastatinHydroxyAcidSodiumSalt
  • Packaging25mg
  • Price$370
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CN2-0539-M025 Simvastatin.sodiumsalt ≥98%(HPLC) 25mg $180 2021-12-16 Buy
ApexBio Technology C4426 Simvastatin(sodiumsalt) 25mg $146 2021-12-16 Buy
ApexBio Technology C4426 Simvastatin(sodiumsalt) 100mg $341 2021-12-16 Buy
Arctom AS010751 Simvastatinsodiumsalt 95% 1g $732 2021-12-16 Buy
Biosynth Carbosynth FS65168 Simvastatin Na 10mg $45 2021-12-16 Buy
Biosynth Carbosynth FS65168 Simvastatin Na 50mg $158 2021-12-16 Buy
Cayman Chemical 10010345 Simvastatin (sodium salt) ≥98% 1mg $36 2024-03-01 Buy
Cayman Chemical 10010345 Simvastatin (sodium salt) ≥98% 5mg $155 2024-03-01 Buy
Cayman Chemical 10010345 Simvastatin (sodium salt) ≥98% 10mg $274 2024-03-01 Buy
Cayman Chemical 10010345 Simvastatin (sodium salt) ≥98% 25mg $595 2024-03-01 Buy
TRC S485050 SimvastatinHydroxyAcidSodiumSalt 25mg $370 2021-12-16 Buy

Properties

Melting point :>122°C (dec.)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form :White powder solid.
color :White to Pale Beige
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H303 May be harmfulif swallowed Acute toxicity,oral Category 5 P312
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Simvastatin is a competitive inhibitor of HMG-CoA reductase (Ki = 0.12 nM). Simvastatin reduces plasma cholesterol levels in rats and dogs when administered at doses of 1.2 and 8 mg/kg, respectively. Simvastatin suppresses TNF-induced NF-κB activation (IC50 = ~13 μM) and potentiates apoptosis in human myeloid leukemia cells. It also inhibits glutathione peroxidase 4 (GPX4) activity, increases malondialdehyde (MDA) levels, and induces ferroptosis in MDA-MB-231 and MCF-7 breast cancer cells. Formulations containing simvastatin have been used in the treatment of dyslipidemias.

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