| | 5812-07-7 Basic information More.. |
| Product Name: | SU 4312 | | Synonyms: | 3-[[(4-DIMETHYLAMINO)PHENYL]METHYLENE]-1,3-DIHYDRO-2H-INDOL-2-ONE;3-(4-DIMETHYLAMINOBENZYLIDENYL)-2-INDOLINONE;3-[[(4-Dimethylamino)phenyl]methylene]-1,3-dihydro-2H-indol-2-one, E/Z mixture;NSC 86429;SU 4312;2H-Indol-2-one, 3-[[4-(dimethylamino)phenyl]methylene]-1,3-dihydro;(Z)-3-(4-(DIMETHYLAMINO)BENZYLIDENE)INDOLIN-2-ONE;SU4312(NSC86429) | | CAS: | 5812-07-7 | | MF: | C17H16N2O | | MW: | 264.32 | | EINECS: | | | Mol File: | 5812-07-7.mol |  |
Use
ChEBI: A member of the class of oxindoles that is 3-methyleneoxindole in which one of the hydrogens of the methylene group has been replaced by a p-(dimethylamino)phenyl group. SU 4312 is a vascular endothelial growth factor (VEGF) receptor protein
yrosine kinase 1/2 and platelet derived growth factor (PDGF) receptor inhibitor. It also inhibits the neuronal nitric oxide synthase (NOS) and exhibits neuroprotection against NO-mediated neurotoxicity.
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5812-07-7
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