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Product Name:RO 20-1724
Synonyms:4-(3-BUTOXY-4-METHOXYBENZYL)-2-IMIDAZOLIDINONE;4-(3-BUTOXY-4-METHOXYBENZYL)-2-IMIDAZOLIDONE;4-(3-BUTOXY-4-METHOXY-BENZYL)IMIDAZOLIDIN-2-ONE;4-[(3-BUTOXY-4-METHOXYPHENYL)METHYL]-2-IMIDAZOLIDINONE;4-(3-BUTOXY-4-METHOXYPHENYL)METHYL-2-IMIDAZOLIDONE;ro 20-172;RO 20-1724;4-[(3-Butoxy-4-methoxyphenyl)methyl]imidazolidin-2-one
CAS:29925-17-5
MF:C15H22N2O3
MW:278.35
EINECS:
Mol File:29925-17-5.mol
29925-17-5

Use

Ro 20-1724 is a cell-permeable, cAMP-specific phosphodiesterase type IV (PDE4) inhibitor (IC50 = 2 μM). It weakly inhibits PDE3 with a Ki value greater than 25 μM. Ro 20-1724 inhibits the release of cytokines and other inflammatory signals as well as prevents the development of reactive oxygen species. It is often used to study cAMP-related functions in vascular cells.

RO 20-1724 manufacturers

  • RO 20-1724
  • US $15.00-10.00 / KG
  • 2021-08-12
  • CAS:29925-17-5
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
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