| | 130-26-7 Basic information More.. |
| Product Name: | Clioquinol | | Synonyms: | 5-chloro-7-iodo-8-quinolino;7-Iodo-5-chloroxine;8-Quinolinol, 5-chloro-7-iodo-;ala-quin;Alchloquin;alchoquin;alioform;Amebil | | CAS: | 130-26-7 | | MF: | C9H5ClINO | | MW: | 305.5 | | EINECS: | 204-984-4 | | Mol File: | 130-26-7.mol |  |
Use
Clioquinol, a halogenated hydroxyquinoline derivative, was
introduced into medicine around 1900 as a topical antiseptic and in 1934 oral
preparations for the treatment of amoebic dysentery and simple diarrhoea became
available. By 1964 its use in Japan had been associated with cases of sub-acute
myelo-optic neuropathy (SMON) which reached epidemic proportions resulting in
its withdrawal there in 1970. Although relatively few cases of SMON were
documented elsewhere, clioquinol was subsequently withdrawn from use in many
countries and placed under prescription control in others. It was phased out
worldwide by the major manufacturer between 1983 and 1985 on grounds of
obsolescence. No adequately controlled evidence was ever generated to
demonstrate that clioquinol is effective in bacterial or viral diarrhoea. However,
products containing clioquinol and related halogenated hydroxyquinolines
continue to be used in some tropical and subtropical countries where amoebiasis
remains endemic. Other amoebocides are preferred in the WHO Model List of
Essential Drugs.
(Reference: (WHODI) WHO Drug Information, 77.1, 9, 1977)
- Clioquinol
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- US $50.00 / kg
- 2023-08-02
- CAS:130-26-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 1000tons
- Clioquinol
-
- US $220.00-186.00 / KG
- 2022-09-27
- CAS:130-26-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 9000kg/per week
- Clioquinol
-
- US $220.00-186.00 / KG
- 2022-09-27
- CAS:130-26-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 9000kg/per week
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130-26-7
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