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Product Name:CHARTREUSIN
Synonyms:CHARTREUSIN;antibioticx-465a;nsc5159;u-7257;chartreusin from streptomyces*chartreusis;LAMBDAMYCIN;10-[[6-Deoxy-2-O-(6-deoxy-3-O-methyl-α-D-galactopyranosyl)-β-D-galactopyranosyl]oxy]-6-hydroxy-1-methylbenzo[h][1]benzopyrano[5,4,3-cde][1]benzopyran-5,12-dione;LaMbdaMycin, NSC 5159, 747, 1293, X465A, G 261A
CAS:6377-18-0
MF:C32H32O14
MW:640.59
EINECS:
Mol File:6377-18-0.mol
6377-18-0

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Chartreusin is an antitumor antibiotic that binds to GC-rich tracts in DNA, with a clear preference for B-DNA over Z-DNA. It inhibits RNA synthesis and causes single-strand scission of DNA via the formation of free radicals. Chartreusin is also a potent inhibitor of topoisomerase II.

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