ARG-PRO-LYS-PRO-GLN-GLN-PHE
| 中文名称 | ARG-PRO-LYS-PRO-GLN-GLN-PHE |
|---|---|
| 中文同义词 | 1-7-P 物质;P物质片段1-7;神经肽P物质SUBSTANCE P (1-7);物质P(1-7)、SUBSTANCE P(1-7);P物质片段1-7 TFA盐 |
| 英文名称 | SUBSTANCE P (1-7) |
| 英文同义词 | RPKPQQF;SUBSTANCE P (1-7);SUBSTANCE P FRAGMENT 1-7;ARG-PRO-LYS-PRO-GLN-GLN-PHE;H-ARG-PRO-LYS-PRO-GLN-GLN-PHE-OH;L-Arg-L-Pro-L-Lys-L-Pro-L-Gln-L-Gln-L-Phe-OH;L-Arg-L-Pro-L-Lys-L-Pro-L-Glu(NH2)-L-Glu(NH2)-L-Phe-OH;PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2: PKPQQFFGLM-NH2 |
| CAS号 | 68060-49-1 |
| 分子式 | C41H65N13O10 |
| 分子量 | 900.04 |
| EINECS号 | |
| 相关类别 | 多肽;生化试剂;其他生化试剂;标准品;Peptide |
| Mol文件 | 68060-49-1.mol |
| 结构式 |  |
ARG-PRO-LYS-PRO-GLN-GLN-PHE 性质
| 密度 | 1.49±0.1 g/cm3(Predicted) |
|---|---|
| 储存条件 | −20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 酸度系数(pKa) | 3.49±0.10(Predicted) |
Substance P(1-7) 是神经肽P物质 (SP) 的片段。Substance P(1-7) 可对孤束核产生抑制和缓和作用。
Substance P (1-7) is found to act as a very potent antagonist against the SP-induced responses and is formed locally in the nigra after SP injection. It is proposed that Substance P (1-7) is an endogenous modulator of SP actions. Injection of low doses of Substance P (1-7) (1.0-4.0 pM simultaneously with SP or SP(5-11) (0.1 nM), reduce aversive behaviours induced by SP or SP(5- 11) significantly. These results indicate that SP(1-7) formed endogenously could modulate the actions of SP or SP(5-11) in the spinal cord.
安全信息
| WGK Germany | 3 |
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| 提供商 | 语言 |
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英文
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