Company Name: |
ChemStrong Scientific Co.,Ltd
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Tel: |
0755-0755-66853366 13670046396 |
Email: |
sales@chem-strong.com |
Products Intro: |
Product Name:Busulfan Impurity 10 CAS:5539-53-7 Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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Company Name: |
Shanghai Kewel Chemical Co., Ltd.
|
Tel: |
021-64609169 18901607656 |
Email: |
greensnown@163.com |
Products Intro: |
Product Name:Busulfan Impurity 8 CAS:5539-53-7 Purity:95+ HPLC; Package:10mg;25mg;50mg;100mg
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Company Name: |
TOSUN PHARM
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Tel: |
020-61855200 13326451905 |
Email: |
2881290884@qq.com |
Products Intro: |
Product Name:Busulfan Impurity 6 CAS:5539-53-7 Purity:98%以上 Package:10mg;50mg;100mg等多种规格 Remarks:REF-B03009
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Company Name: |
QUALITY CONTROL SOLUTIONS LTD.
|
Tel: |
13670046396 |
Email: |
ORDERS@QCSRM.COM |
Products Intro: |
Product Name:Busulfan Impurity 8 Purity:95% HPLC Package:10MG;25MG;50MG;100MG
|
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| acetyl Methanesulfonate Basic information |
Product Name: | acetyl Methanesulfonate | Synonyms: | NSC 158252;acetyl Methanesulfonate;Methanesulfonyl acetate;Busulfan Impurity 10;Acetic acid, anhydride with methanesulfonic acid;Busulfan Impurity 6 | CAS: | 5539-53-7 | MF: | C3H6O4S | MW: | 138.14 | EINECS: | | Product Categories: | | Mol File: | 5539-53-7.mol | |
| acetyl Methanesulfonate Chemical Properties |
Boiling point | 56 °C(Press: 0.01 Torr) | density | 1.346±0.06 g/cm3(Predicted) | storage temp. | Hygroscopic, Refrigerator, under inert atmosphere | solubility | Chloroform (Sparingly) | form | Oil | color | Yellow | Stability: | Extremely Moisture Sensitive |
| acetyl Methanesulfonate Usage And Synthesis |
Uses | Acetyl Methanesulfonate, is an impurity of Busulfan (B689900), an alkylating agent with antileukemic activity. Antineoplastic. | Purification Methods | The main impurity is methanesulfonic acid. Reflux it with redistilled acetyl chloride for 6-10hours, i.e. until no further HCl is absorbed in a trap, and exclude moisture. Distil off excess of AcCl and carefully distil it below 0.001mm with the bath temperature below 120o to give the anhydride as a pale yellow oil which solidifies below 0o. Below ~130o it gives the disulfonic anhydride, and above ~130o polymers are formed, and it is used for cleaving ethers [Preparation, IR, NMR: Karger & Mazur J Org Chem 36 528, 532 1971]. [Beilstein 2 H 166, 2 III 349.] |
| acetyl Methanesulfonate Preparation Products And Raw materials |
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