N-Boc-PEG4-bromide
中文名称 | N-Boc-PEG4-bromide |
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中文同义词 | 叔丁氧羰基四聚乙二醇溴;N-BOC-PEG4-BROMIDE,叔丁氧羰基-四聚乙二醇-溴代;氨基叔丁氧羰基-四聚乙二醇-溴;溴-四聚乙二醇-氨基叔丁酯;(14-溴-3,6,9,12-四氧杂十四烷基)氨基甲酸叔丁酯;叔丁氧羰基-PEG4-溴;16-溴-5,8,11,14-四氧杂-2-氮杂十六烷酸叔丁酯;化合物N-BOC-PEG5-BROMIDE |
英文名称 | N-Boc-PEG4-bromide |
英文同义词 | N-Boc-PEG4-bromide;BocNH-PEG4-CH2CH2Br;N-Boc-PEG5-bromide;Br-PEG4-NHBoc;5,8,11,14-Tetraoxa-2-azahexadecanoic acid, 16-bromo-, 1,1-dimethylethyl ester;tert-butyl (14-bromo-3,6,9,12-tetraoxatetradecyl)carbamate;ADC,antibody-drug,PROTAC Linkers,ADC Linkers,N-Boc-PEG-5-bromide,cleavable,inhibit,conjugates,Inhibitor,N Boc PEG5 bromide,NBocPEG5bromide,Antibody-drug conjugates linkers;tert-butyl N-[2-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]ethyl]carbamate |
CAS号 | 1392499-32-9 |
分子式 | C15H30BrNO6 |
分子量 | 400.31 |
EINECS号 | |
相关类别 | 助剂 |
Mol文件 | 1392499-32-9.mol |
结构式 |
N-Boc-PEG4-bromide 性质
沸点 | 459.3±40.0 °C(Predicted) |
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密度 | 1.223±0.06 g/cm3(Predicted) |
溶解度 | 溶于二氯甲烷 |
酸度系数(pKa) | 12.23±0.46(Predicted) |
Cleavable
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PEGs
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Alkyl/ether
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PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.