| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:(-)-Umbellulone
CAS:546-78-1
Purity:>=98% (HPLC) Package:5MG Remarks:SML0782-5MG
|
| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Email: |
sales@dcchemicals.com |
| Products Intro: |
Product Name:Umbellulone
CAS:546-78-1
Purity:98% HPLC Package:100mg，250mg，1g
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing@energy-chemical.com |
| Products Intro: |
Product Name:(-)-Umbellulone >=98% (HPLC)
CAS:546-78-1
Purity:NULL Package:5mg Remarks:NULL
|
|
| | [1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one Basic information |
| | [1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one Chemical Properties |
| storage temp. | -20°C | | solubility | DMSO : 250 mg/mL (1664.23 mM; Need ultrasonic) | | color | colorless to light brown |
| | [1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one Usage And Synthesis |
| Definition | ChEBI: Umbellulone is a ketone. | | Biochem/physiol Actions | (-)-Umbellulone, isolated from the"headache tree" Umbellularia californica Nutt, is a selective activator of Transient Receptor Potential Anykrin 1 (TRPA1) channels. (-)-Umbellulone activates TRPA1 channels on nociceptive trigeminal afferents, resulting in release of CGRP and CGRP-mediated neurogenic vasodilatation, causing a painful cold sensation and headache/migraine. |
| | [1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one Preparation Products And Raw materials |
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