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| | Ilaprazole sodium Basic information |
| Product Name: | Ilaprazole sodium | | Synonyms: | Ilaprazole sodium;IY-81149 sodium;Ilaprazole sodium USP/EP/BP;Sodium ilaprazole;oral,Ilaprazole,acid,ulcers,IY 81149,inhibit,IY-81149,TOPK,gastric,Inhibitor,cancer,Ilaprazole sodium,IY81149,pump,Proton Pump;Ilaprazole Sodium Salt | | CAS: | 172152-50-0 | | MF: | C19H19N4NaO2S | | MW: | 390.44 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 172152-50-0.mol |  |
| | Ilaprazole sodium Chemical Properties |
| storage temp. | 4°C, protect from light | | CAS DataBase Reference | 172152-50-0 |
| | Ilaprazole sodium Usage And Synthesis |
| Uses | After oral administration, Ilaprazole sodium selectively enters the gastric parietal cells and is converted into an active metabolite of sulfenamide, which interacts with the sulfhydryl group on the H+/K+-ATPase to form a covalent combination of disulfide bonds, irreversibly inhibiting H+/K+- ATPase, which inhibits gastric acid secretion. | | in vitro | On cumulation of 14C-aminopyrine in histamine stimulated parietal cells, the IC 50 of Ilaprazole (IY-81149) sodium is 9 nM. | | target | | Target | Value | Proton pump
() | | H(+) /K(+)-ATPase
(in rabbit parietal cell preparation) | 6 μM |
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| | Ilaprazole sodium Preparation Products And Raw materials |
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