| Company Name: |
Amatek Scientific Co. Ltd.
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| Tel: |
0512-56316828 |
| Email: |
info@amateksci.com |
| Products Intro: |
Product Name:mPEG16-CH2CH2COOH
CAS:2346581-96-0
Purity:97% HPLC Package:1g;5g;25g;100g
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| Company Name: |
Alpha Biopharmaceuticals Co., Ltd
|
| Tel: |
0411-39042497 |
| Email: |
sales@alphabiopharm.com |
| Products Intro: |
Product Name:m-PEG17-acid
Purity:98% HPLC Package:1g,5g,25g,100g,500g,1kg Remarks:F0571
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| | m-PEG17-acid Basic information |
| Product Name: | m-PEG17-acid | | Synonyms: | m-PEG17-acid;mPEG16-CH2CH2COOH/2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-Heptadecaoxatripentacontan-53-oic acid | | CAS: | 2346581-96-0 | | MF: | C36H72O19 | | MW: | 808.95 | | EINECS: | | | Product Categories: | | | Mol File: | 2346581-96-0.mol |  |
| | m-PEG17-acid Chemical Properties |
| Boiling point | 763.8±60.0 °C(Predicted) | | density | 1.114±0.06 g/cm3(Predicted) | | pka | 4.28±0.10(Predicted) |
| | m-PEG17-acid Usage And Synthesis |
| Biological Activity | m-PEG17-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | m-PEG17-acid Preparation Products And Raw materials |
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