SCHIZOZYGINE

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Company Name: Fluorochem Ltd  
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Company Name: Fluorochem Ltd.  
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SCHIZOZYGINE Basic information
Product Name:SCHIZOZYGINE
Synonyms:SCHIZOZYGINE
CAS:
MF:C20H20N2O3
MW:336.38
EINECS:
Product Categories:
Mol File:Mol File
SCHIZOZYGINE Structure
SCHIZOZYGINE Chemical Properties
Melting point 192-4°C
Safety Information
MSDS Information
SCHIZOZYGINE Usage And Synthesis
DescriptionThe major alkaloid obtained from the bark and roots of Schizozygia caffaeoides (Boj.) Baill. The base has [α]23D + 15.5° (c 1.0, CHC13) and gives an ultraviolet spectrum having absorption maxima at 269 and 313 mil. The alkaloid possesses both antipyretic and broncholytic properties. When hydrogenated in AcOH in the presence of Pt02 it yields the dihydro derivative, m.p. 190-1°C;[α]24D + 29.4° (c 1.0, CHCI3). Hydrogenation with LiAIH4, however, gives deoxoschizozygine, m.p. 213-233°C (dec.); [α]26D + 82.9° (c 1.0, CHCI3). The two reduction processes are protected by patents.
ReferencesRenner, Kernweisz., Experientia, 19,244 (1963)
Structure:
Renner., Lloydia, 27,406 (1964)
Renner., Swiss Patent 451,182,15 May 1968
Renner., Swiss Patent 451,183,15 May 1968
SCHIZOZYGINE Preparation Products And Raw materials
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