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| | (+)-JQ1 PA Basic information |
| Product Name: | (+)-JQ1 PA | | Synonyms: | (+)-JQ1 PA;JQ1 PA;JQ-1 PA;JQ 1 PA;(6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-N-2-propyn-1-yl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide;PubChem ID: 134821687;6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-2,3,9-trimethyl-N-2-propyn-1-yl-, (6S)-;(+)-JQ1 PA;inhibit,(+) JQ1 PA,(+)-JQ1 PA,Inhibitor,Epigenetic Reader Domain,(+)JQ1 PA,(+)-JQ-1 PA;(S)-2-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(prop-2-yn-1-yl)acetamide | | CAS: | 2115701-93-2 | | MF: | C22H20ClN5OS | | MW: | 437.95 | | EINECS: | | | Product Categories: | | | Mol File: | 2115701-93-2.mol |  |
| | (+)-JQ1 PA Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml; Ethanol: 25 mg/ml | | form | A crystalline solid |
| | (+)-JQ1 PA Usage And Synthesis |
| Biological Activity | (+)-JQ1 PA is a derivative of the bromodomain and extra terminal domain (BET) inhibitor JQ1 with an IC50 value of 10.4 nM. | | in vitro | (+)-JQ1 PA is a derivative of JQ1, which is the inhibitor of BET. The IC 50 of (+)-JQ1 PA for BET is 10.4 nM, and the IC 50 of JQ1 is 14.3 nM in MV4;11 cells. | | target | | | storage | Store at -20°C |
| | (+)-JQ1 PA Preparation Products And Raw materials |
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