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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788 |
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jkinfo@jkchemical.com |
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Product Name:HyMenialdisine Analogue #1 CAS:693222-51-4 Package:10Mg,1Mg
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TargetMol Chemicals Inc.
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15002134094 |
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marketing@targetmol.com |
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Product Name:Hymenialdisine Analogue #1 CAS:693222-51-4 Purity:详情请点击官网 Package:1 mg
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Company Name: |
CLEARSYNTH LABS LTD.
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+91-22-45045900 |
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sales@clearsynth.com |
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Product Name:Hymenialdisine Analogue #1 CAS:693222-51-4
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| HYMENIALDISINE ANALOGUE #1 Basic information |
Product Name: | HYMENIALDISINE ANALOGUE #1 | Synonyms: | HYMENIALDISINE ANALOGUE #1;5-(2-Amino-5-oxo-1,5-dihydroimidazol-4-ylidene)-3,4,5,10-tetrahydro-2H-azepino[3,4-b]indol-1-one;5-(2-Amino-5-oxo-1,5-dihydroimidazol-4-ylidene)-3,4,5,10-tetrahydro-2H-azepino[3,4-β]indol-1-one;Azepino[3,4-b]indol-1(2H)-one, 5-(2-amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-3,4,5,10-tetrahydro- | CAS: | 693222-51-4 | MF: | C15H13N5O2 | MW: | 295.3 | EINECS: | | Product Categories: | Protein Kinase Inhibitors and Activators;Tyrosine Kinase Inhibitors | Mol File: | 693222-51-4.mol | |
| HYMENIALDISINE ANALOGUE #1 Chemical Properties |
density | 1.73±0.1 g/cm3(Predicted) | storage temp. | -20°C Freezer | solubility | DMSO (Slightly) | form | Solid | pka | 14.41±0.20(Predicted) | color | Light Yellow to Yellow | CAS DataBase Reference | 693222-51-4 |
| HYMENIALDISINE ANALOGUE #1 Usage And Synthesis |
Chemical Properties | Light Yellow Solid | Uses | The indole derivative of Hymenialdisine, a potent inhibitor of a variety of kinases including MEK-1, GSK-3Β, and CKI. It also exhibits inhibition of the G2 cell cycle checkpoint at the micromolar concentrations. This compound exhibits very potent inhibition of Chk2 activity in the low nanomolar range (IC50=8nM). Exhibits an increased selectivity for the checkpoint kinases over natural Hymenialdisine. |
| HYMENIALDISINE ANALOGUE #1 Preparation Products And Raw materials |
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