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Carbamic acid, N-[(2R,3S)-2-methyl-4-oxo-3-oxetanyl]-, 5-phenylpentyl ester

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Carbamic acid, N-[(2R,3S)-2-methyl-4-oxo-3-oxetanyl]-, 5-phenylpentyl ester Suppliers list
Company Name: Aladdin Scientific
Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:ARN 077 (enantiomer)
CAS:1439366-88-7
Purity:99% Package:$350.9/5mg;$580.9/10mg;Bulk package Remarks:99%
Carbamic acid, N-[(2R,3S)-2-methyl-4-oxo-3-oxetanyl]-, 5-phenylpentyl ester Basic information
Product Name:Carbamic acid, N-[(2R,3S)-2-methyl-4-oxo-3-oxetanyl]-, 5-phenylpentyl ester
Synonyms:Carbamic acid, N-[(2R,3S)-2-methyl-4-oxo-3-oxetanyl]-, 5-phenylpentyl ester;ARN 077 (enantiomer)
CAS:1439366-88-7
MF:C16H21NO4
MW:291.34
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Product Categories:
Mol File:1439366-88-7.mol
Carbamic acid, N-[(2R,3S)-2-methyl-4-oxo-3-oxetanyl]-, 5-phenylpentyl ester Structure
Carbamic acid, N-[(2R,3S)-2-methyl-4-oxo-3-oxetanyl]-, 5-phenylpentyl ester Chemical Properties
Boiling point 474.4±44.0 °C(Predicted)
density 1.16±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
pka10.45±0.40(Predicted)
Safety Information
MSDS Information
Carbamic acid, N-[(2R,3S)-2-methyl-4-oxo-3-oxetanyl]-, 5-phenylpentyl ester Usage And Synthesis
Biological ActivityARN 077 enantiomer (19) is the less active enantiomer of ARN 077, with an IC50 of 3.53 μM for rat NAAA[1].
References[1]. Stefano Ponzano, et al. Synthesis and structure-activity relationship (SAR) of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters, a class of potent N-acylethanolamine acid amidase (NAAA) inhibitors. J Med Chem. 2013 Sep 12;56(17):6917-34.
Carbamic acid, N-[(2R,3S)-2-methyl-4-oxo-3-oxetanyl]-, 5-phenylpentyl ester Preparation Products And Raw materials
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