Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
Tel: |
400-9205774 |
Email: |
sales@glpbio.cn |
Products Intro: |
Product Name:Carbaprostacyclin methyl ester CAS:69552-55-2 Purity:>98% Package:1mg;10mg;50mg;100mg;
|
Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
Tel: |
18818260767 |
Email: |
sales@chemegen.com |
Products Intro: |
Product Name:Carbaprostacyclin methyl ester CAS:69552-55-2 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
Tel: |
021-65675885 18964387627 |
Email: |
customer_service@efebio.com |
Products Intro: |
Product Name:Carbaprostacyclin methyl ester Exclusive CAS:69552-55-2 Purity:98% Package:500μg;1mg;5mg
|
Company Name: |
Cayman Chemical Company
|
Tel: |
(800) 364-9897 |
Email: |
cayman@caymanchem.com |
Products Intro: |
Product Name:Carbaprostacyclin methyl ester CAS:69552-55-2 Package:>=98% Remarks:9000183
|
|
| Carbaprostacyclin methyl ester Basic information |
Product Name: | Carbaprostacyclin methyl ester | Synonyms: | Carbaprostacyclin methyl ester;Carbaprostacyclin methyl ester Exclusive;Pentanoic acid, 5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-1-octen-1-yl]-2(1H)-pentalenylidene]-, methyl ester, (5E)- | CAS: | 69552-55-2 | MF: | C22H36O4 | MW: | 364.52 | EINECS: | | Product Categories: | | Mol File: | 69552-55-2.mol | |
| Carbaprostacyclin methyl ester Chemical Properties |
Boiling point | 479.2±45.0 °C(Predicted) | density | 1.128±0.06 g/cm3(Predicted) | solubility | DMF: 10 mg/ml; DMSO: 5 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): .1 mg/ml | pka | 14.56±0.20(Predicted) |
| Carbaprostacyclin methyl ester Usage And Synthesis |
Description | Carbaprostacyclin is a stable analog of prostacyclin (prostaglandin I2) which can activate the prostacyclin receptor or PPARδ.1,2,3 Carbaprostacyclin methyl ester is a more lipid soluble form of carbaprostacyclin. As a result, it may more readily enter cells to activate PPARδ. The biological activities of carbaprostacyclin methyl ester have not been studied. | References | 1. Aubert, J., Ailhaud, G., and Negrel, R. Evidence for a novel regulatory pathway activated by (carba)prostacyclin in preadipose and adipose cells FEBS Lett. 397(1),117-121(1996). 2. Armstrong, R.A., Lawrence, R.A., Jones, R.L., et al. Functional and ligand binding studies suggest heterogeneity of platelet prostacyclin receptors Br. J. Pharmacol. 97,657-668(1989). 3. Kurtz, M., Capobianco, E., Martínez, N., et al. Carbaprostacyclin, a PPARδ agonist, ameliorates excess lipid accumulation in diabetic rat placentas Life Sci. 86,781-790(2010). |
| Carbaprostacyclin methyl ester Preparation Products And Raw materials |
|