Carbaprostacyclin methyl ester

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Company Name: Shanghai Hongye Biotechnology Co. Ltd  
Tel: 400-9205774
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Products Intro: Product Name:Carbaprostacyclin methyl ester
CAS:69552-55-2
Purity:>98% Package:1mg;10mg;50mg;100mg;
Company Name: Hangzhou Synstar pharmaceutical Technology CO.,Ltd  
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Products Intro: Product Name:Carbaprostacyclin methyl ester
CAS:69552-55-2
Purity:0.98 Package:100mg、500mg、1g、5g
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
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Products Intro: Product Name:Carbaprostacyclin methyl ester
CAS:69552-55-2
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
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Products Intro: Product Name:Carbaprostacyclin methyl ester Exclusive
CAS:69552-55-2
Purity:98% Package:500μg;1mg;5mg
Company Name: Cayman Chemical Company  
Tel: (800) 364-9897
Email: cayman@caymanchem.com
Products Intro: Product Name:Carbaprostacyclin methyl ester
CAS:69552-55-2
Package:>=98% Remarks:9000183
Carbaprostacyclin methyl ester Basic information
Product Name:Carbaprostacyclin methyl ester
Synonyms:Carbaprostacyclin methyl ester;Carbaprostacyclin methyl ester Exclusive;Pentanoic acid, 5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-1-octen-1-yl]-2(1H)-pentalenylidene]-, methyl ester, (5E)-
CAS:69552-55-2
MF:C22H36O4
MW:364.52
EINECS:
Product Categories:
Mol File:69552-55-2.mol
Carbaprostacyclin methyl ester Structure
Carbaprostacyclin methyl ester Chemical Properties
Boiling point 479.2±45.0 °C(Predicted)
density 1.128±0.06 g/cm3(Predicted)
solubility DMF: 10 mg/ml; DMSO: 5 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): .1 mg/ml
pka14.56±0.20(Predicted)
Safety Information
MSDS Information
Carbaprostacyclin methyl ester Usage And Synthesis
DescriptionCarbaprostacyclin is a stable analog of prostacyclin (prostaglandin I2) which can activate the prostacyclin receptor or PPARδ.1,2,3 Carbaprostacyclin methyl ester is a more lipid soluble form of carbaprostacyclin. As a result, it may more readily enter cells to activate PPARδ. The biological activities of carbaprostacyclin methyl ester have not been studied.
References1. Aubert, J., Ailhaud, G., and Negrel, R. Evidence for a novel regulatory pathway activated by (carba)prostacyclin in preadipose and adipose cells FEBS Lett. 397(1),117-121(1996).
2. Armstrong, R.A., Lawrence, R.A., Jones, R.L., et al. Functional and ligand binding studies suggest heterogeneity of platelet prostacyclin receptors Br. J. Pharmacol. 97,657-668(1989).
3. Kurtz, M., Capobianco, E., Martínez, N., et al. Carbaprostacyclin, a PPARδ agonist, ameliorates excess lipid accumulation in diabetic rat placentas Life Sci. 86,781-790(2010).
Carbaprostacyclin methyl ester Preparation Products And Raw materials
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