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| | RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT Basic information |
| | RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT Chemical Properties |
| Melting point | 220°C dec. | | storage temp. | -20°C Freezer | | solubility | Aqueous Acid (Slightly), Water (Slightly, Sonicated) | | form | Solid | | color | Off-White to Pale Beige | | Stability: | Hygroscopic |
| | RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT Usage And Synthesis |
| Description | Ribavirin 5''-monophosphate inhibits viral DNA and RNA replication in vitro via the strong competitive inhibition of inosine monophosphate dehydrogenase (IMPDH), with a reported Ki value of 270 nM, and thus inhibits guanosine triphosphate synthesis. This agent, a metabolite of the prodrug ribavirin , exhibits broad-spectrum antiviral activity, particularly against myxoviruses. The antiviral effects of ribavirin require conversion to the monophosphate form via adenosine kinase. The anti-HIV activity of ribavirin in cultured human lymphocytes, as well as the anti-influenza activity of this prodrug in MDCK cells, have been attributed to ribavirin 5''-monophosphate. | | Chemical Properties | RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT is Solid | | Uses | A metabolite of Ribavirin. | | Uses | RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT is used as an antiviral agent |
| | RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT Preparation Products And Raw materials |
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