107767-58-8
中文名称 | 107767-58-8 |
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中文同义词 | 化合物 T14075 |
英文名称 | A 802715 |
英文同义词 | A 802715;1H-Purine-2,6-dione, 3,7-dihydro-1-(5-hydroxy-5-methylhexyl)-3-methyl-7-propyl-;A 802715,A802715 |
CAS号 | 107767-58-8 |
分子式 | C16H26N4O3 |
分子量 | 322.4 |
EINECS号 | |
相关类别 | |
Mol文件 | 107767-58-8.mol |
结构式 |
107767-58-8 性质
沸点 | 526.7±56.0 °C(Predicted) |
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密度 | 1.22±0.1 g/cm3(Predicted) |
储存条件 | Store at -20°C |
溶解度 | 二甲基亚砜:190 mg/ml(589.33 mM) |
酸度系数(pKa) | 15.28±0.29(Predicted) |
The toxicity of the methylxanthine derivative A802715 is determined against the two human melanoma lines, Be11 and MeWo, and against the two human squamous cell carcinoma lines, 4197 and 4451, by vital dye staining assay. A802715 has a TD 50 of 0.9-1.1 mM and is the most toxic. In p53 wt cells BrdU incorporations show that the irradiation-induced suppression of S-phase entry is strongly enhanced by A802715. A802715 prolongs the G 2 /M block or remain ineffective depending on the p53 status of the cell line.
安全信息
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024/04/30 | HY-U00142 | 107767-58-8 A-802715 | 107767-58-8 | 1mg | 1600元 |
2024/04/30 | HY-U00142 | 107767-58-8 A-802715 | 107767-58-8 | 10mM * 1mLin DMSO | 2270元 |