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| | LINOLEOYLETHANOLAMIDE Basic information |
| Product Name: | LINOLEOYLETHANOLAMIDE | | Synonyms: | N-(2-HYDROXYETHYL)-9Z, 12Z-OCTADECADIENAMIDE;ODNHETOH;LEA;n-(2-hydroxyethyl)-,(z,z)-12-octadecadienamide;(9Z,12Z)-N-(2-hydroxyethyl)octadeca-9,12-dien-1-amide;9,12-Octadecadienamide, N-(2-hydroxyethyl)-, (9Z,12Z)-;Linoleic ethanolamine;(9Z,12Z)-N-(2-Hydroxyethyl)-9,12-octadecadienamide | | CAS: | 68171-52-8 | | MF: | C20H37NO2 | | MW: | 323.51 | | EINECS: | 269-029-6 | | Product Categories: | Cannabinoids;Neurobiology;Pharmacologicals | | Mol File: | 68171-52-8.mol |  |
| | LINOLEOYLETHANOLAMIDE Chemical Properties |
| Melting point | 38-40 °C | | Boiling point | 499.1±38.0 °C(Predicted) | | density | 0.926±0.06 g/cm3(Predicted) | | Fp | 14 °C | | storage temp. | -20°C | | solubility | DMF:25.0(Max Conc. mg/mL);77.27(Max Conc. mM)
DMSO:25.0(Max Conc. mg/mL);77.27(Max Conc. mM)
Ethanol:50.0(Max Conc. mg/mL);154.55(Max Conc. mM) | | form | ethanol solution | | pka | 14.49±0.10(Predicted) | | Stability: | Light Sensitive, Temperature Sensitive | | LogP | 6.003 (est) | | EPA Substance Registry System | 9,12-Octadecadienamide, N-(2-hydroxyethyl)-, (9Z,12Z)- (68171-52-8) |
| | LINOLEOYLETHANOLAMIDE Usage And Synthesis |
| Uses | N-Linoleoylethanolamine reduces lipopolysaccharide-induced inflammation in macrophages and reduces inflammation in ameliorates 2,4-dinitrofluorobenzene-induced contact dermatitis. N-Linoleoylethanolamine inhibits NF-κB signaling and may be used as a therapeutic agent against contact dermatitis.Linoleoyl ethanolamide is an endocannabinoid detected in porcine brain. | | Definition | ChEBI: An N-(long-chain-acyl)ethanolamine that is the ethanolamide of linoleic acid. | | Biochem/physiol Actions | A structural analogue of the endogenous cannabinoid receptor ligand anandamide. |
| | LINOLEOYLETHANOLAMIDE Preparation Products And Raw materials |
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