GALANIN (1-13) - BRADYKININ (2-9) AMIDE
| 中文名称 | GALANIN (1-13) - BRADYKININ (2-9) AMIDE |
|---|---|
| 中文同义词 | M35肽;甘丙肽(1-13)-缓激肽(2-9)酰胺 |
| 英文名称 | M35 |
| 英文同义词 | M35;H-GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG-NH2;GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG-NH2;GALANIN (1-13)-BRADYKININ (2-9) AMIDE;GWTLNSAGYLLGPPPGFSPFR-NH2;GALANIN FRAGMENT (1-13)-BRADYKININ*FRAGMENT (2-9)AM;Galanin receptorligand M35;Galanin (1-13)-Bradykinin (2-9), amide, M35 |
| CAS号 | 142846-71-7 |
| 分子式 | C107H153N27O26 |
| 分子量 | 2233.52 |
| EINECS号 | |
| 相关类别 | 多肽;Peptides for Cell Biology;Galanin receptor;Peptide;Galanins;Neuropeptides |
| Mol文件 | 142846-71-7.mol |
| 结构式 |  |
GALANIN (1-13) - BRADYKININ (2-9) AMIDE 性质
| 储存条件 | −20°C |
|---|---|
| 溶解度 | 溶于二甲基亚砜 |
| 形态 | 固体 |
Kd: 0.1 nM (galanin receptor)
Ki: 0.11 nM (human galanin receptor type 1), 2.0 nM (human galanin receptor type 2)
Galanin Receptor Ligand M35 has a dual effect on the galanin mediated inhibition of Forskolin stimulated cyclic AMP production in Rin m 5F cells. Co-applied with galanin (10 nM), Galanin Receptor Ligand M35 at low concentrations (1 nM) is able to reverse the inhibitory effect of galanin. But when present at higher concentrations (15 and 30 nM), Galanin Receptor Ligand M35 acts as a galanin receptor agonist, inhibiting the forskolin stimulated production of cAMP.
Galanin Receptor Ligand M35 (6 nM/10 μL; i.c.v.) improves the ability of the male Sprague-Dnwley rats to acquire the swim maze task.
安全信息
| 安全说明 | 22-24/25 |
|---|---|
| WGK Germany | 3 |
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/04/30 | HY-P1840 | GALANIN (1-13) - BRADYKININ (2-9) AMIDE Galanin Receptor Ligand M35 | 142846-71-7 | 1mg | 2000元 |
| 2024/04/30 | HY-P1840 | GALANIN (1-13) - BRADYKININ (2-9) AMIDE Galanin Receptor Ligand M35 | 142846-71-7 | 10mg | 6510元 |