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(S)-7-(Dimethylamino)-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one

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(S)-7-(Dimethylamino)-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one Basic information
Product Name:(S)-7-(Dimethylamino)-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one
Synonyms:(S)-7-(Dimethylamino)-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one;N-Methylcolchamine;N-Methyldemecolcine
CAS:7336-44-9
MF:C22H27NO5
MW:0
EINECS:
Product Categories:
Mol File:7336-44-9.mol
(S)-7-(Dimethylamino)-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one Structure
(S)-7-(Dimethylamino)-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one Chemical Properties
Melting point 206-8°C
Safety Information
ToxicityLD50 intramuscular in mouse: 200mg/kg
MSDS Information
(S)-7-(Dimethylamino)-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one Usage And Synthesis
DescriptionA colchicine type alkaloid, N-methylcolchamine occurs in Merendera robusta Bge. It is laevorotatory having a specific rotation of [α]D - 109° (CHC13). The structure has been established from spectroscopic data and by comparison with colchamine.
ReferencesSalen et at., Collect. Czech. Chem. Commun., 28, 3413 (1963)
Trudykulov, Yusupov, Sadykov, Khim. Prir. Soedin., (1972)
Yusupov, Tr. Tashkent Nauch. Uzbek SSR, 20, 24 (1972)
(S)-7-(Dimethylamino)-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one Preparation Products And Raw materials
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