- Buclosamide
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- $0.37 / 1g
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2021-01-06
- CAS:575-74-6
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 1kg/10kg/100kg
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| | Buclosamide Basic information |
| Product Name: | Buclosamide | | Synonyms: | Fungit;Buclosamide;N-butyl-4-chlorosalicylamide;N-Butyl-4-chloro-2-hydroxybenzamide;3004 BUCLOSAMIDE;Demycin;Buclosamidum;Benzamide, N-butyl-4-chloro-2-hydroxy- | | CAS: | 575-74-6 | | MF: | C11H14ClNO2 | | MW: | 227.69 | | EINECS: | 209-390-9 | | Product Categories: | | | Mol File: | 575-74-6.mol |  |
| | Buclosamide Chemical Properties |
| Melting point | 90-92° | | Boiling point | 366.6±32.0 °C(Predicted) | | density | 1.1769 (rough estimate) | | refractive index | 1.5500 (estimate) | | pka | 7.43±0.35(Predicted) |
| | Buclosamide Usage And Synthesis |
| Originator | Fungit,Dragon | | Definition | ChEBI: Buclosamide is a member of salicylamides. | | Manufacturing Process | 4-Chloro-2-hydroxy-benzoic acid n-butyl-amide
A mixture consisting of 114 g of 4-chloro-2-hydroxy-benzoic acid n-butylester,
64 grams of methanol and 130 g of n-butyl-amine is heated for 22
hours at 80°C; then the parts volatile up to 130°C are distilled off under
reduced pressure. The residue crystallizing in the cold is dissolved in 200 ml
of methanol and the solution obtained is slowly added dropwise and while
stirring into dilute hydrochloric acid, if necessary, after treatment with animal
charcoal. The precipitate which is at first semi-solid soon crystallizes
completely. It is filtered with suction, washed with dilute hydrochloric acid,
then thoroughly washed again with water, and the product obtained in good
yield is dried in the air. After having been recrystallized twice from carbon
tetrachloride the 4-chloro-2-hydroxybenzene acid n-butylamide melts at 90-
92°C. | | Therapeutic Function | Antifungal |
| | Buclosamide Preparation Products And Raw materials |
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