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| | S-[2-(diethylamino)ethyl] alpha-phenylbenzeneethanethioate hydrochloride Basic information |
| | S-[2-(diethylamino)ethyl] alpha-phenylbenzeneethanethioate hydrochloride Chemical Properties |
| | S-[2-(diethylamino)ethyl] alpha-phenylbenzeneethanethioate hydrochloride Usage And Synthesis |
| Originator | Trocinate,Poythress,US,1950 | | Manufacturing Process | The following procedure is described in US Patent 2,510,773: To an ice-cold
solution of 13.3 grams of 2-diethylaminoethanethiol in 100 cc of dry benzene
is slowly added a solution of 23.05 grams of diphenylacetyl chloride in 200 cc
of dry benzene. The mixture is stirred 2 hours, then heated to dissolve the
fine white solid that is formed. Upon cooling 31.3 grams of 2-
diethylaminoethyl diphenylthiolacetate hydrochloride precipitates. It
recrystallizes from a mixture of benzene and petroleum ether (BP 60° to
70°C) as rosettes of tiny needles and melts at 129° to 130°C. From a mixture
of absolute ethanol and ethyl acetate it recrystallizes as large, almost
transparent prisms. | | Brand name | Tifenamil is INN. | | Therapeutic Function | Spasmolytic |
| | S-[2-(diethylamino)ethyl] alpha-phenylbenzeneethanethioate hydrochloride Preparation Products And Raw materials |
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