N-desMethyl EnzalutaMide

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CAS:1242137-16-1
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N-desMethyl EnzalutaMide manufacturers

N-desMethyl EnzalutaMide Basic information
Product Name:N-desMethyl EnzalutaMide
Synonyms:N-desMethyl EnzalutaMide;4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluorobenzaMide;Enzalutamide impurity B;Enzalutamide Impurity 2;N-desmethyl MDV 3100;N-desmethyl MDV3100;N-desmethyl MDV-3100;N-DESMETHYL MDV3100;N-DESMETHYL MDV 3100;N-DESMETHYL MDV-3100
CAS:1242137-16-1
MF:C20H14F4N4O2S
MW:450.41
EINECS:
Product Categories:Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:1242137-16-1.mol
N-desMethyl EnzalutaMide Structure
N-desMethyl EnzalutaMide Chemical Properties
Melting point >230oC (dec.)
Boiling point 572.4±60.0 °C(Predicted)
density 1.55±0.1 g/cm3(Predicted)
storage temp. Amber Vial, Refrigerator
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Very Slightly, Heated)
pka14.86±0.50(Predicted)
form Solid
color White to Off-White
Stability:Light Sensitive
Safety Information
MSDS Information
N-desMethyl EnzalutaMide Usage And Synthesis
Uses4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzamide is used in the treatment of disorders involving androgen, estrogen and progesterone receptors.
UsesN-desMethyl EnzalutaMide is used in the treatment of disorders involving androgen, estrogen and progesterone receptors.
DefinitionChEBI: N-desmethylenzalutamide is a benzamide obtained by formal condensation of the carboxy group of 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluorobenzoic acid with ammonia. It has a role as an antineoplastic agent and an androgen antagonist. It is a member of benzamides, an imidazolidinone, a nitrile, a thiocarbonyl compound, a member of (trifluoromethyl)benzenes and a member of monofluorobenzenes.
N-desMethyl EnzalutaMide Preparation Products And Raw materials
Tag:N-desMethyl EnzalutaMide(1242137-16-1) Related Product Information
Enzalutamide Enzalutamide Enzalutamide carboxylic acid Oxathiolan 5fu-.B. 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzoic acid methyl ester EnzalutaMide IMpurity methyl 2-fluoro-4-((1-methoxy-2-methyl-1-oxopropan-2-yl)amino)benzoate 4-Bromo-2-fluorobenzoic acid 4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide 4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide Methyl 4-bromo-2-fluorobenzoate 4-(2-CYANOPROPAN-2-YLAMINO)-2-FLUORO-N-METHYLBENZAMIDE [2H6]-Enzalutamide Enzalutamide Impurity 7 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile Enzalutamide Impurity 7 4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N- 4-amino-2-fluoro-N-methylbenzamide